Angiotensin-converting enzyme (ACE) inhibitors are widely used to reduce blood pressure.
Here, we examined if an ACE is important for the antibacterial effectiveness of neutrophils. …

Renal fibrosis is the final common pathway of chronic kidney diseases. Lymphatic vessel (LV)
proliferation is found in human renal diseases and other fibrotic diseases, suggesting that …

This retrospective cohort study examined the roles of inflammation in acute kidney injury (AKI).
Serum albumin and C-reactive protein (CRP) were used as markers of inflammation. …

Background Cardiothoracic ratio by chest radiography is commonly used to assess volume
status. Little is known about the relationships between cardiothoracic ratio and the incidence …

The cause of most hypertensive disease is unclear, but inflammation appears critical in disease
progression. However, how elevated blood pressure initiates inflammation is unknown, …

Multiple disorders underlie the development of CRS. Current treatment options include renin–angiotensin
system blockade and volume control, but remain limited. A multidisciplinary …

We previously reported that brain atrophy was more severe and progressed more rapidly in
patients with end-stage kidney disease on peritoneal dialysis (PD) than those with non-…

Diabetic nephropathy is a major cause of end-stage renal disease in developed countries.
While angiotensin-converting enzyme (ACE) inhibitors are used to treat diabetic nephropathy, …

Vascular calcification (VC) is a critical complication in patients with chronic kidney disease (CKD).
The effects of spironolactone (SPL), a mineralocorticoid receptor (MR) antagonist, on …

Association of preoperative regular use of anti-adrenergic agents with postoperative acute
kidney injury (AKI) and with trajectory of kidney function after AKI is still unknown. In a …