Multiple angiogenesis inhibitors have been therapeutically validated in preclinical cancer
models, and several in clinical trials. Here we report that angiogenesis inhibitors targeting the …

Acute-phase response factor (APRF) is a transcription factor that blnds to the Interfeukln-6 (IL-@-responsive
elements identlfled In the promoters of various acutephase protein genes. …

A mouse model involving the human papillomavirus type-16 oncogenes develops cervical
cancers by lesional stages analogous to those in humans. In this study the angiogenic …

Tumor hypoxia has been considered to be a potential therapeutic problem because it renders
solid tumors more resistant to sparsely ionizing radiation (IR) and chemotherapeutic drugs…

p57 KIP2 is a potent tight-binding inhibitor of several G 1 cyclin/Cdk complexes, and is a
negative regulator of cell proliferation 1 , 2 . The gene encoding p57 KIP2 is located at 11p15.5 (…

In the RIP1-Tag2 mouse model of pancreatic islet carcinoma, angiogenesis is switched on
in a discrete premalignant stage of tumor development, persisting thereafter. Signaling …

We have developed a wind turbine system that consists of a diffuser shroud with a broad-ring
flange at the exit periphery and a wind turbine inside it. The flanged-diffuser shroud plays a …

Ensemble-averaged and phase-locked flow patterns in various tip clearances of two axial
compressor rotors were obtained by aperiodic multisampling technique with a hot wire in the …

The breakdown of tip leakage vortex has been investigated on a low-speed axial compressor
rotor with moderate blade loading. Effects of the breakdown on the rotor aerodynamics are …

The revascularisation and remodelling of allografts used to replace the anterior cruciate
ligament in the canine knee were studied by microangiographic, histological and biomechanical …