Cysteine hydropersulfide (CysSSH) occurs in abundant quantities in various organisms, yet
little is known about its biosynthesis and physiological functions. Extensive persulfide …

Autophagy is mostly a nonselective bulk degradation system within cells. Recent reports
indicate that autophagy can act both as a protector and killer of the cell depending on the stage …

Trypsin activity is properly suppressed in the pancreatic acinar cells under normal conditions.
A small amount of trypsinogen is converted to active trypsin and inactivated by pancreatic …

We used a custom-made comparative genomic hybridization array (aCGH; average probe
interval 254 bp) to screen 33 malignant mesothelioma (MM) biopsies for somatic copy number …

… Pass, Mitsuru Emi, Masaki Nasu, Ian Pagano, Ryuji Yamamoto, Tomoko Hashimoto-Tamaoki,
Masaki Ohmuraya, Keisuke Goto, Kavita Y. Sarin, Angela Bononi, Andrea Napolitano …

Background & Aims: Serine protease inhibitor Kazal type 1 (SPINK1), which is structurally
similar to epidermal growth factor, is thought to inhibit trypsin activity and to prevent pancreatitis…

Objectives: To evaluate the clinical applicability of the determination of disseminated
intravascular coagulation (DIC) parameters in acute pancreatitis. Methods: The subjects for this …

New neurons, continuously added in the adult olfactory bulb (OB) and hippocampus, are
involved in information processing in neural circuits. Here, we show that synaptic pruning of …

Serine protease inhibitor, Kazal type 1 (SPINK1) is expressed not only in normal human
pancreatic acinar cells but also in a variety of pancreatic ductal neoplasms. There are structural …

Background Fusobacterium nucleatum (F. nucleatum) is a gut microbe implicated in
gastrointestinal tumorigenesis. Predicting the chemotherapeutic response is critical to developing …