Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection

…, M Baba, KA Datsenko, M Tomita… - Molecular systems …, 2006 - embopress.org
We have systematically made a set of precisely defined, single‐gene deletions of all
nonessential genes in Escherichia coli K‐12. Open‐reading frame coding regions were replaced …

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

…, HD Spence, J Stelling, K Takahashi, M Tomita… - …, 2003 - academic.oup.com
Motivation: Molecular biotechnology now makes it possible to build elaborate systems
models, but the systems biology community needs information standards if models are to be …

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

…, T Lockett, JM Clarke, DL Topping, M Tomita… - Nature, 2013 - nature.com
Gut commensal microbes shape the mucosal immune system by regulating the differentiation
and expansion of several types of T cell 1 , 2 , 3 , 4 , 5 . Clostridia, a dominant class of …

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

S Kosugi, M Hasebe, M Tomita… - Proceedings of the …, 2009 - National Acad Sciences
The cell cycle-dependent nucleocytoplasmic transport of proteins is predominantly regulated
by CDK kinase activities; however, it is currently difficult to predict the proteins thus …

E-CELL: software environment for whole-cell simulation.

M Tomita, K Hashimoto, K Takahashi… - Bioinformatics …, 1999 - academic.oup.com
MOTIVATION: Genome sequencing projects and further systematic functional analyses of
complete gene sets are producing an unprecedented mass of molecular information for a wide …

[PDF][PDF] An efficient augmented-context-free parsing algorithm

M Tomita - Computational linguistics, 1987 - aclanthology.org
The algorithm parses a sentence strictly from left to right on-line, that is, it starts parsing as
soon as the user types in the first word of a sentence, without waiting for completion of the …

Whole-cell simulation: a grand challenge of the 21st century

M Tomita - TRENDS in Biotechnology, 2001 - cell.com
Study of the cell will never be complete unless its dynamic behavior is understood. The
complex behavior of the cell cannot be determined or predicted unless a computer model of the …

[HTML][HTML] Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

M Sugimoto, DT Wong, A Hirayama, T Soga, M Tomita - Metabolomics, 2010 - Springer
Saliva is a readily accessible and informative biofluid, making it ideal for the early detection
of a wide range of diseases including cardiovascular, renal, and autoimmune diseases, viral …

High-temperature superconductor bulk magnets that can trap magnetic fields of over 17 tesla at 29 K

M Tomita, M Murakami - Nature, 2003 - nature.com
Large-grain high-temperature superconductors of the form RE-Ba-Cu-O (where RE is a rare-earth
element) can trap magnetic fields of several tesla at low temperatures, and so can be …

[BOOK][B] Efficient parsing for natural language: a fast algorithm for practical systems

M Tomita - 1985 - books.google.com
Parsing Efficiency is crucial when building practical natural language systems.'Ibis is especially
the case for interactive systems such as natural language database access, interfaces to …