Expanded polyglutamine repeats have been proposed to cause neuronal degeneration in
Huntington's disease (HD) and related disorders, through abnormal interactions with other …

Excessive activation of the nuclear enzyme, poly(ADP-ribose) polymerase-1 (PARP-1) plays
a prominent role in various of models of cellular injury. Here, we identify poly(ADP-ribose) (…

Neuroimaging studies of autism have shown abnormalities in the limbic system and
cerebellar circuits and additional sites. These findings are not, however, specific or consistent …

Parkinson's disease (PD) is a common neurodegenerative movement disorder. Whereas the
majority of PD cases are sporadic, rare genetic defects have been linked to this prevalent …

This paper aims to rethink creative city theory by analyzing urban regeneration processes in
Japan through cultural creativity and social inclusion. The impact of Florida’s theory has led …

Parkinson's disease (PD) is the most common neurodegenerative movement disorder and
is characterized pathologically by degeneration of catecholaminergic neurons of the …

The metabolism of poly(ADP-ribose) (PAR) is critical for genomic stability in multicellular
eukaryotes. Here, we show that the failure to degrade PAR by means of disruption of the murine …

Indirect mechanisms are implicated in the pathogenesis of the dementia associated with
human immunodeficiency virus-type 1 (HIV-1) infection. Proinflammatory molecules such as …

The aim of this study was to investigate the effects of the point-spread function (PSF) and
time-of-flight (TOF) on improving 18 F-FDG PET/CT images in relation to reconstruction …

Congenital hypomyelinating disorders are a heterogeneous group of inherited
leukoencephalopathies characterized by abnormal myelin formation. We have recently reported a …