Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

…, C Freeman, BJ Hamdorf, RT Baker, MJ Harris… - Nature medicine, 1999 - nature.com
The endoglycosidase heparanase is an important in the degradation of the extracellular matrix
by invading cells, notably metastatic tumor cells and migrating leukocytes. Here we report …

Bioelectric signaling as a unique regulator of development and regeneration

MP Harris - Development, 2021 - journals.biologists.com
It is well known that electrical signals are deeply associated with living entities. Much of our
understanding of excitable tissues is derived from studies of specialized cells of neurons or …

Conditional modeling and the jitter method of spike resampling

A Amarasingham, MT Harrison… - Journal of …, 2012 - journals.physiology.org
The existence and role of fine-temporal structure in the spiking activity of central neurons is
the subject of an enduring debate among physiologists. To a large extent, the problem is a …

Dual-purpose cereals: can the relative influences of management and environment on crop recovery and grain yield be dissected?

MT Harrison, JR Evans, H Dove… - Crop and Pasture …, 2011 - CSIRO Publishing
Growing cereal crops for the dual-purposes (DP) of livestock forage during the early vegetative
stages and harvesting grain at maturity has been practised for decades. It follows that …

Brazil's family health strategy—delivering community-based primary care in a universal health system

J Macinko, MJ Harris - New England Journal of Medicine, 2015 - Mass Medical Soc
Brazil's national health system has developed and rapidly scaled up an approach to primary
care that relies on lay community health agents and interdisciplinary care teams to provide …

Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

C Chiang, Y Litingtung, MP Harris, BK Simandl… - Developmental …, 2001 - Elsevier
The secreted protein encoded by the Sonic hedgehog (Shh) gene is localized to the posterior
margin of vertebrate limb buds and is thought to be a key signal in establishing anterior–…

[HTML][HTML] GFDL's CM2 global coupled climate models. Part I: Formulation and simulation characteristics

…, SM Griffies, R Gudgel, MJ Harrison… - Journal of …, 2006 - journals.ametsoc.org
The formulation and simulation characteristics of two new global coupled climate models
developed at NOAA's Geophysical Fluid Dynamics Laboratory (GFDL) are described. The …

Weakening of tropical Pacific atmospheric circulation due to anthropogenic forcing

…, AT Wittenberg, IM Held, A Leetmaa, MJ Harrison - Nature, 2006 - nature.com
Since the mid-nineteenth century the Earth's surface has warmed 1 , 2 , 3 , and models indicate
that human activities have caused part of the warming by altering the radiative balance of …

[HTML][HTML] GFDL's ESM2 global coupled climate–carbon earth system models. Part I: Physical formulation and baseline simulation characteristics

…, W Cooke, KA Dunne, MJ Harrison… - Journal of …, 2012 - journals.ametsoc.org
… Adcroft, A., RW Hallberg, and MJ Harrison, 2008: A finite volume discretization of the
pressure gradient force using analytic integration. Ocean Modell., 22, 106–113, doi:10.1016/j.ocemod.2008.02.001 …

Behavior-dependent short-term assembly dynamics in the medial prefrontal cortex

S Fujisawa, A Amarasingham, MT Harrison… - Nature …, 2008 - nature.com
Although short-term plasticity is believed to play a fundamental role in cortical computation,
empirical evidence bearing on its role during behavior is scarce. Here we looked for the …