We have come a long way in the last years of developing analytical strategies in metabolomics.
We have seen huge progress in tackling multiplatform measurement, data analysis, data …

Prostate cancer ( PC a) has a broad spectrum of clinical behavior; hence, biomarkers are
urgently needed for risk stratification. Here, we aim to find potential biomarkers for risk …

The leading first‐in‐class ruthenium‐complex BOLD‐100 currently undergoes clinical phase‐II
anticancer evaluation. Recently, BOLD‐100 is identified as anti‐Warburg compound. The …

Oxidative stress and reactive oxygen species (ROS) are central to many physiological and
pathophysiological processes. However, due to multiple technical challenges, it is hard to …

The molecular study of fat cell development in the human body is essential for our understanding
of obesity and related diseases. Mesenchymal stem/stromal cells (MSC) are the ideal …

Tumor spheroids are important model systems due to the capability of capturing in vivo tumor
complexity. In this work, the experimental design of metabolomics workflows using three-…

Cellular energy metabolism is reprogrammed in cancer to fuel proliferation. In oncological
therapy, treatment resistance remains an obstacle and is frequently linked to metabolic …

Resistance development is a major obstacle for platinum-based chemotherapy, with the
anticancer drug oxaliplatin being no exception. Acquired resistance is often associated with …

When performing chromatography-mass spectrometry-based nontargeted metabolomics, or
exposomics, one of the key steps in the analysis is to obtain MS1-based feature tables. Inapt …

We have efficiently produced collagen-rich microstructures in fibroblast multicellular
spheroids (MCSs) as a three-dimensional in vitro tissue analog to investigate silver (Ag) …