User profiles for Mateusz M. Tomczyk

Mateusz Tomczyk

Post-doc, Department of Chemistry, Silesian University of Technology
Verified email at polsl.pl
Cited by 107

Mitochondrial sirtuin-3 (SIRT3) prevents doxorubicin-induced dilated cardiomyopathy by modulating protein acetylation and oxidative stress

MM Tomczyk, KG Cheung, B Xiang… - Circulation: Heart …, 2022 - Am Heart Assoc
Background: High doses of doxorubicin put cancer patients at risk for developing dilated
cardiomyopathy. Previously, we showed that doxorubicin treatment decreases SIRT3 (sirtuin 3), …

Carbon quantum dots from amino acids revisited: Survey of renewable precursors toward high quantum-yield blue and green fluorescence

A Kolanowska, G Dzido, M Krzywiecki, MM Tomczyk… - ACS …, 2022 - ACS Publications
Carbon quantum dots (CQDs) were synthesized via a green, one-step hydrothermal method.
As CQD precursors, nine amino acids of different structural descriptors (negatively/…

Nonnutritive sweetener consumption during pregnancy, adiposity, and adipocyte differentiation in offspring: evidence from humans, mice, and cells

MB Azad, A Archibald, MM Tomczyk, A Head… - International journal of …, 2020 - nature.com
Background Obesity often originates in early life, and is linked to excess sugar intake.
Nonnutritive sweeteners (NNS) are widely consumed as “healthier” alternatives to sugar, yet …

[HTML][HTML] The cardiac lipidome in models of cardiovascular disease

MM Tomczyk, VW Dolinsky - Metabolites, 2020 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death worldwide. There are numerous
factors involved in the development of CVD. Among these, lipids have an important role in …

Synthesis of amide and sulfonamide substituted N-aryl 6-aminoquinoxalines as PFKFB3 inhibitors with improved physicochemical properties

…, A Stachowicz, MM Tomczyk… - Bioorganic & Medicinal …, 2019 - Elsevier
In oncology, the “Warburg effect” describes the elevated production of energy by glycolysis
in cancer cells. The ubiquitous and hypoxia-induced 6-phosphofructo-2-kinase/fructose-2,6-…

[HTML][HTML] Multiwalled carbon nanotube hybrids as MRI contrast agents

N Kuźnik, MM Tomczyk - Beilstein Journal of Nanotechnology, 2016 - beilstein-journals.org
Magnetic resonance imaging (MRI) is one of the most commonly used tomography techniques
in medical diagnosis due to the non-invasive character, the high spatial resolution and …

Discovery and Structure–Activity Relationships of N‐Aryl 6‐Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors

…, A Stachowicz, MM Tomczyk… - …, 2019 - Wiley Online Library
Energy and biomass production in cancer cells are largely supported by aerobic glycolysis
in what is called the Warburg effect. The process is regulated by key enzymes, among which …

[HTML][HTML] Surprising Solid-State ESIPT Emission from Apparently Ordinary Salicyliden Glycinates Schiff Bases

MM Tomczyk, Ł Przypis, T Shiraki, J Kusz… - International journal of …, 2022 - mdpi.com
Excited-State Intramolecular Photon Transfer (ESIPT) is known for the geometry-related
phenolic and imine groups. The Schiff bases formed upon condensation of salicyl aldehyde and …

Amalgamation of complex iron(III) ions and iron nanoclusters with MWCNTs as a route to potential T2 MRI contrast agents

N Kuźnik, MM Tomczyk, M Wyskocka… - International Journal …, 2015 - Taylor & Francis
Iron-filled multiwall carbon nanotubes (Fe@MWCNTs) were functionalized toward a variety
of potential magnetic resonance imaging contrast agents. Oxidized Fe@MWNCTs were …

Fe3+ ions anchored to Fe@ o-MWCNTs as double impact T2 MRI contrast agents

N Kuźnik, MM Tomczyk, S Boncel, AP Herman… - Materials Letters, 2014 - Elsevier
Fe3+ ions were anchored via complexation onto the oxidized multiwall carbon nanotubes
containing encapsulated iron-based nanoparticles (Fe@O-MWCNTs) yielding hybrids Fe(III)/…