The spike protein (S) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
required for cell entry and is the primary focus for vaccine development. In this study, we …

The paradigmatic disordered protein tau plays an important role in neuronal function and
neurodegenerative diseases. To disentangle the factors controlling the balance between …

MiR-21 is being gradually more and more recognized as a molecule regulating bone tissue
homeostasis. However, its function is not fully understood due to the dual role of miR-21 on …

Recent waves of COVID-19 correlate with the emergence of the Delta and the Omicron
variant. We report that the Spike trimer acts as a highly dynamic molecular caliper, thereby …

A new theoretical survey of proteins' resistance to constant speed stretching is performed for
a set of 17 134 proteins as described by a structure-based model. The proteins selected …

The primary immunological target of COVID-19 vaccines is the SARS-CoV-2 spike (S)
protein. S is exposed on the viral surface and mediates viral entry into the host cell. To identify …

Circular or ring-like actin structures play important roles in various developmental and
physiological processes. Commonly, these rings are composed of actin filaments and myosin …

Animal development entails the organization of specific cell types in space and time, and
spatial patterns must form in a robust manner. In the zebrafish spinal cord, neural progenitors …

Polysaccharides (carbohydrates) are key regulators of a large number of cell biological
processes. However, precise biochemical or genetic manipulation of these often complex …

Background Progression of senile osteoporosis is associated with deteriorated regenerative
potential of bone marrow-derived mesenchymal stem/stromal cells (BMSCs). According to …