Severe Acute Respiratory Syndrome coronavirus 2 (SARS‐CoV‐2) is rapidly spreading
around the world. There is no existing vaccine or proven drug to prevent infections and stop …

SARS-CoV-2 Nsp15 is a uridine-specific endoribonuclease with C-terminal catalytic domain
belonging to the EndoU family that is highly conserved in coronaviruses. As …

The genome of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
coronavirus has a capping modification at the 5′-untranslated region (UTR) to prevent its …

The replication transcription complex (RTC) from the virus SARS-CoV-2 is responsible for
recognizing and processing RNA for two principal purposes. The RTC copies viral RNA for …

Pattern recognition receptors are critical for the detection of invading microorganisms. They
activate multiple pathways that lead to the induction of proinflammatory responses and …

MCPIP1, also known as Regnase-1, is a ribonuclease crucial for regulation of stability of
transcripts related to inflammatory processes. Here, we report that MCPIP1 acts as an …

Serial synchrotron crystallography enables the study of protein structures under physiological
temperature and reduced radiation damage by collection of data from thousands of crystals…

Monoclonal antibodies (mAbs) are the basis of treatments and diagnostics for pathogens and
other biological phenomena. We conducted a structural characterization of mAbs against …

Emergence of Enterobacteriaceae harboring metallo‐β‐lactamases (MBL) has raised global
threats due to their broad antibiotic resistance profiles and the lack of effective inhibitors …

CCAAT/enhancer-binding protein beta (C/EBPβ) is a transcription factor controlling a broad
range of genes essential for homeostasis, including genes related to immune functions, …