The Saccharomyces cerevisiae Spo11 protein catalyses DNA double-strand breaks (DSBs)
that initiate meiotic recombination. The model plant Arabidopsis thaliana possesses at least …

Meiosis is the cell division that reshuffles genetic information between generations. Recently,
much progress has been made in understanding this process; in particular, the …

Meiotic crossovers (COs) have intriguing patterning properties, including CO interference,
the tendency of COs to be well-spaced along chromosomes, and heterochiasmy, the marked …

The success of the first meiotic division relies (among other factors) on the formation of
bivalents between homologous chromosomes, the monopolar orientation of the sister …

The SPO11 protein catalyzes the formation of meiotic DNA double strand breaks (DSBs)
and is homologous to the A subunit of an archaeal topoisomerase (topo VI). Topo VI are …

In numerous species, the formation of meiotic crossovers is largely under the control of a group
of proteins known as ZMM. Here, we identified a new ZMM protein, HEI10, a RING finger-…

Meiotic crossovers are limited in number and are prevented from occurring close to each
other by crossover interference. In many species, crossover number is subject to sexual …

Background: Crossovers are essential for the completion of meiosis. Recently, two pathways
of crossover formation have been identified on the basis of distinct genetic controls. In one …

In budding yeast meiosis, the formation of class I interference-sensitive crossovers requires
the ZMM proteins. These ZMM proteins are essential in forming a mature synaptonemal …

Meiotic recombination is initiated by the formation of numerous DNA double-strand breaks (DSBs)
catalysed by the widely conserved Spo11 protein. In Saccharomyces cerevisiae, …