User profiles for Mati Joshua

Mati Joshua

The Hebrew University of Jerusalem
Verified email at mail.huji.ac.il
Cited by 1698

Cerebellar climbing fibers encode expected reward size

N Larry, M Yarkoni, A Lixenberg, M Joshua - elife, 2019 - elifesciences.org
10.7554/eLife.46870.001 Climbing fiber inputs to the cerebellum encode error signals that
instruct learning. Recently, evidence has accumulated to suggest that the cerebellum is also …

Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions

…, BN Taylor, MA Hughes, A McKinney, M Joshua… - Nature …, 2018 - nature.com
The prevailing model of cerebellar learning states that climbing fibers (CFs) are both driven
by, and serve to correct, erroneous motor output. However, this model is grounded largely in …

The dynamics of dopamine in control of motor behavior

M Joshua, A Adler, H Bergman - Current opinion in neurobiology, 2009 - Elsevier
The basal ganglia are known to control behavior using reward information; however, recent
experiments have revealed that the basal ganglia contribute to the processing of salient non-…

Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic …

M Joshua, A Adler, R Mitelman, E Vaadia… - Journal of …, 2008 - Soc Neuroscience
Midbrain dopaminergic neurons (DANs) typically increase their discharge rate in response
to appetitive predictive cues and outcomes, whereas striatal cholinergic tonically active …

[HTML][HTML] A tale of two species: neural integration in zebrafish and monkeys

M Joshua, SG Lisberger - Neuroscience, 2015 - Elsevier
Selection of a model organism creates tension between competing constraints. The recent
explosion of modern molecular techniques has revolutionized the analysis of neural systems …

[PDF][PDF] Emergence of context-dependent variability across a basal ganglia network

SC Woolley, R Rajan, M Joshua, AJ Doupe - Neuron, 2014 - cell.com
Context dependence is a key feature of cortical-basal ganglia circuit activity, and in songbirds
the cortical outflow of a basal ganglia circuit specialized for song, LMAN, shows striking …

Quantifying the isolation quality of extracellularly recorded action potentials

M Joshua, S Elias, O Levine, H Bergman - Journal of neuroscience …, 2007 - Elsevier
There have been many approaches to the problem of detection and sorting of extra-cellularly
recorded action potentials, but only a few methods actually quantify the quality of this …

Encoding of probabilistic rewarding and aversive events by pallidal and nigral neurons

M Joshua, A Adler, B Rosin… - Journal of …, 2009 - journals.physiology.org
Previous studies have rarely tested whether the activity of high-frequency discharge (HFD)
neurons of the basal ganglia (BG) is modulated by expectation, delivery, and omission of …

[PDF][PDF] Synchronization of midbrain dopaminergic neurons is enhanced by rewarding events

M Joshua, A Adler, Y Prut, E Vaadia, JR Wickens… - Neuron, 2009 - cell.com
The basal ganglia network is divided into two functionally related subsystems: the neuromodulators
and the main axis. It is assumed that neuromodulators adjust cortico-striatal coupling…

Statistical properties of pauses of the high-frequency discharge neurons in the external segment of the globus pallidus

S Elias, M Joshua, JA Goldberg, G Heimer… - Journal of …, 2007 - Soc Neuroscience
The neurons of many basal ganglia nuclei, including the external and internal globus
pallidus (GPe and GPi, respectively) and the substantia nigra pars reticulata (SNr) are …