[HTML][HTML] The structural variation landscape in 492 Atlantic salmon genomes

…, D Robledo, MP Kent, LL Røsæg, MM Holen… - Nature …, 2020 - nature.com
Structural variants (SVs) are a major source of genetic and phenotypic variation, but remain
challenging to accurately type and are hence poorly characterized in most species. We …

[HTML][HTML] Comparative regulomics supports pervasive selection on gene dosage following whole genome duplication

GB Gillard, L Grønvold, LL Røsæg, MM Holen… - Genome Biology, 2021 - Springer
Background Whole genome duplication (WGD) events have played a major role in eukaryotic
genome evolution, but the consequence of these extreme events in adaptive genome …

Gene family expansion and functional diversification of chitinase and chitin synthase genes in Atlantic salmon (Salmo salar)

MM Holen, G Vaaje-Kolstad, MP Kent… - G3: Genes, Genomes …, 2023 - academic.oup.com
Chitin is one of the most abundant polysaccharides in nature, forming important structures
in insects, crustaceans, and fungal cell walls. Vertebrates on the other hand are generally …

Aromatic-Mediated Carbohydrate Recognition in Processive Serratia marcescens Chitinases

…, AG Hamre, P Wildberger, MM Holen… - The Journal of …, 2016 - ACS Publications
Microorganisms use a host of enzymes, including processive glycoside hydrolases, to
deconstruct recalcitrant polysaccharides to sugars. Processive glycoside hydrolases closely …

The effect of dietary chitin on Atlantic salmon (Salmo salar) chitinase activity, gene expression, and microbial composition

MM Holen, SR Sandve, TN Harvey, Y Jin, IL Angell… - bioRxiv, 2022 - biorxiv.org
Background Chitin is a common component in the natural diet of many fish, and a range of
chitinases with the potential to down chitin have been identified. Yet whether chitin is …

Thermodynamic Relationships with Processivity in Serratia marcescens Family 18 Chitinases

AG Hamre, S Jana, MM Holen… - The Journal of …, 2015 - ACS Publications
The enzymatic degradation of recalcitrant polysaccharides is accomplished by synergistic
enzyme cocktails of glycoside hydrolases (GHs) and accessory enzymes. Many GHs are …

Comparative regulomics reveals pervasive selection on gene dosage following whole genome duplication

GB Gillard, L Grønvold, LL Røsæg, MM Holen… - Biorxiv, 2020 - biorxiv.org
Whole genome duplication (WGD) events have played a major role in eukaryotic genome
evolution, but the consequence of these extreme events in adaptive genome evolution is still …

Characterization of genes and proteins related to chitin metabolism in Atlantic salmon

MM Holen - 2022 - nmbu.brage.unit.no
Chitin is an insoluble polysaccharide and important component in the extracellular matrix of
invertebrates such as arthropods, algae, and fungi. In vertebrates, the role and significance …

The gastric mucosa of Atlantic salmon (Salmo salar) is abundant in highly active chitinases

M Mengkrog Holen, TR Tuveng, MP Kent… - FEBS Open …, 2024 - Wiley Online Library
Atlantic salmon (Salmo salar) possesses a genome containing 10 genes encoding chitinases,
yet their functional roles remain poorly understood. In other fish species, chitinases have …

Strategies of inorganic and organic trace mineral supplementation in gestating hyperprolific sow diets: effects on the offspring performance and fetal programming

…, F Gonzalez-Solè, M D'Angelo… - Journal of Animal …, 2021 - academic.oup.com
The aim of the present study was to evaluate the effect of trace mineral nutrition on sow
performance, mineral content, and intestinal gene expression of neonate piglets when inorganic …