User profiles for Mats Bemark

Mats Bemark

Verified email at immuno.gu.se
Cited by 3840

Induction of gut IgA production through T cell‐dependent and T cell‐independent pathways

M Bemark, P Boysen, NY Lycke - … of the New York Academy of …, 2012 - Wiley Online Library
The gut immune system protects against mucosal pathogens, maintains a mutualistic
relationship with the microbiota, and establishes tolerance against food antigens. This requires a …

The composition of the gut microbiota shapes the colon mucus barrier

…, A Schütte, A Ermund, P Boysen, M Bemark… - EMBO …, 2015 - embopress.org
Two C57 BL /6 mice colonies maintained in two rooms of the same specific pathogen‐free (
SPF ) facility were found to have different gut microbiota and a mucus phenotype that was …

[HTML][HTML] Translating transitions–how to decipher peripheral human B cell development

M Bemark - Journal of biomedical research, 2015 - ncbi.nlm.nih.gov
During the last two decades our understanding of human B cell differentiation has developed
considerably. Our understanding of the human B cell compartment has advanced from a …

Human intestinal B cells in inflammatory diseases

J Spencer, M Bemark - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
The intestinal lumen contains an abundance of bacteria, viruses and fungi alongside
ingested material that shape the chronically active intestinal immune system from early life to …

[HTML][HTML] Serum-IgG responses to SARS-CoV-2 after mild and severe COVID-19 infection and analysis of IgG non-responders

…, H Axelsson, K Nyström, H Norder, M Bemark… - PloS one, 2020 - journals.plos.org
Background To accurately interpret COVID-19 seroprevalence surveys, knowledge of serum-IgG
responses to SARS-CoV-2 with a better understanding of patients who do not …

Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers

…, E Gärdby, A Stensson, M Bemark… - The Journal of …, 2006 - journals.aai.org
Conflicting findings have recently been presented as to the sites and sources of B cells that
undergo class switch recombination (CSR) to IgA in the gut. In this study we provide …

[PDF][PDF] Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells

…, N Borcherding, JW Yewdell, V Greiff, M Bemark… - Cell reports, 2021 - cell.com
B cell responses are critical for antiviral immunity. However, a comprehensive picture of
antigen-specific B cell differentiation, clonal proliferation, and dynamics in different organs after …

T cell-independent IgA class switch recombination is restricted to the GALT and occurs prior to manifest germinal center formation

…, A Stensson, NY Lycke, M Bemark - The Journal of …, 2010 - journals.aai.org
Recently, we reported that CD40−/− mice, exhibiting exclusively T cell-independent IgA class
switch recombination (CSR), demonstrated near normal levels of IgA plasma cells in the …

[PDF][PDF] Disruption of mouse polymerase ζ (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro

M Bemark, AA Khamlichi, SL Davies, MS Neuberger - Current Biology, 2000 - cell.com
Multiple DNA polymerases exist in eukaryotes. Polymerases α, δ and ε are mainly responsible
for chromosomal DNA replication in the nucleus and are required for proliferation. In …

[HTML][HTML] Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

…, F Ciccarelli, S Heck, SH Kleinstein, M Bemark… - Nature …, 2018 - nature.com
Human memory B cells and marginal zone (MZ) B cells share common features such as the
expression of CD27 and somatic mutations in their IGHV and BCL6 genes, but the …