User profiles for Mats E. Pettersson

Mats Pettersson

Forskare, IMBIM, Uppsala Universitet
Verified email at imbim.uu.se
Cited by 2036

A century after Fisher: time for a new paradigm in quantitative genetics

RM Nelson, ME Pettersson, Ö Carlborg - Trends in Genetics, 2013 - cell.com
Quantitative genetics traces its roots back through more than a century of theory, largely
formed in the absence of directly observable genotype data, and has remained essentially …

[HTML][HTML] Genome-wide effects of long-term divergent selection

AM Johansson, ME Pettersson, PB Siegel… - PLoS …, 2010 - journals.plos.org
To understand the genetic mechanisms leading to phenotypic differentiation, it is important
to identify genomic regions under selection. We scanned the genome of two chicken lines …

[HTML][HTML] Natural CMT2 Variation Is Associated With Genome-Wide Methylation Changes and Temperature Seasonality

…, J De Jonge, SKG Forsberg, ME Pettersson… - PLoS …, 2014 - journals.plos.org
As Arabidopsis thaliana has colonized a wide range of habitats across the world it is an
attractive model for studying the genetic mechanisms underlying environmental adaptation. Here…

SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma

…, E Axelsson, CG Couto, WC Kisseberth, ME Pettersson… - Cancer research, 2018 - AACR
Osteosarcoma is a debilitating bone cancer that affects humans, especially children and
adolescents. A homologous form of osteosarcoma spontaneously occurs in dogs, and its …

A chromosome-level assembly of the Atlantic herring genome—detection of a supergene and other signals of selection

ME Pettersson, CM Rochus, F Han, J Chen… - Genome …, 2019 - genome.cshlp.org
The Atlantic herring is a model species for exploring the genetic basis for ecological adaptation,
due to its huge population size and extremely low genetic differentiation at selectively …

Ecological adaptation in European eels is based on phenotypic plasticity

ED Enbody, ME Pettersson… - Proceedings of the …, 2021 - National Acad Sciences
The relative role of genetic adaptation and phenotypic plasticity is of fundamental importance
in evolutionary ecology [MJ West-Eberhard, Proc. Natl. Acad. Sci. USA 102 (suppl. 1), 6543…

Ecological adaptation in Atlantic herring is associated with large shifts in allele frequencies at hundreds of loci

F Han, M Jamsandekar, ME Pettersson, L Su… - Elife, 2020 - elifesciences.org
Atlantic herring is widespread in North Atlantic and adjacent waters and is one of the most
abundant vertebrates on earth. This species is well suited to explore genetic adaptation due to …

Recurrent convergent evolution at amino acid residue 261 in fish rhodopsin

J Hill, ED Enbody, ME Pettersson… - Proceedings of the …, 2019 - National Acad Sciences
The evolutionary process that occurs when a species colonizes a new environment provides
an opportunity to explore the mechanisms underlying genetic adaptation, which is essential …

Reconstruction of the birth of a male sex chromosome present in Atlantic herring

…, J Chen, A Herpin, ME Pettersson… - Proceedings of the …, 2020 - National Acad Sciences
The mechanisms underlying sex determination are astonishingly plastic. Particularly the
triggers for the molecular machinery, which recalls either the male or female developmental …

[HTML][HTML] Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

…, A Roy, L Haseeb, ME Pettersson, E Sundström… - Genome biology, 2020 - Springer
Background Glioblastoma (GBM) has one of the worst 5-year survival rates of all cancers.
While genomic studies of the disease have been performed, alterations in the non-coding …