User profiles for Matteo Fecchio

Matteo Fecchio

Center for Neurotechnology and Neurorecovery, Department of Neurology, MGH
Verified email at mgh.harvard.edu
Cited by 1761

Stratification of unresponsive patients by an independently validated index of brain complexity

…, M Rosanova, S Sarasso, M Fecchio… - Annals of …, 2016 - Wiley Online Library
Objective Validating objective, brain‐based indices of consciousness in behaviorally
unresponsive patients represents a challenge due to the impossibility of obtaining independent …

[HTML][HTML] TMS combined with EEG: Recommendations and open issues for data collection and analysis

…, S Casarotto, EP Casula, F Farzan, M Fecchio… - Brain Stimulation, 2023 - Elsevier
Transcranial magnetic stimulation (TMS) evokes neuronal activity in the targeted cortex and
connected brain regions. The evoked brain response can be measured with …

[HTML][HTML] Bistability breaks-off deterministic responses to intracortical stimulation during non-REM sleep

…, C Szymanski, G Arnulfo, S Casarotto, M Fecchio… - Neuroimage, 2015 - Elsevier
During non-rapid eye movement (NREM) sleep (stage N3), when consciousness fades,
cortico-cortical interactions are impaired while neurons are still active and reactive. Why is this? …

Quantifying cortical EEG responses to TMS in (un) consciousness

…, AG Casali, S Casarotto, M Fecchio… - Clinical EEG and …, 2014 - journals.sagepub.com
We normally assess another individual’s level of consciousness based on her or his ability
to interact with the surrounding environment and communicate. Usually, if we observe …

[HTML][HTML] Sleep-like cortical OFF-periods disrupt causality and complexity in the brain of unresponsive wakefulness syndrome patients

M Rosanova, M Fecchio, S Casarotto, S Sarasso… - Nature …, 2018 - nature.com
Unresponsive wakefulness syndrome (UWS) patients may retain intact portions of the
thalamocortical system that are spontaneously active and reactive to sensory stimuli but fail to …

[HTML][HTML] The spectral features of EEG responses to transcranial magnetic stimulation of the primary motor cortex depend on the amplitude of the motor evoked …

M Fecchio, A Pigorini, A Comanducci, S Sarasso… - PloS one, 2017 - journals.plos.org
Transcranial magnetic stimulation (TMS) of the primary motor cortex (M1) can excite both
cortico-cortical and cortico-spinal axons resulting in TMS-evoked potentials (TEPs) and motor-…

[HTML][HTML] The rt-TEP tool: real-time visualization of TMS-Evoked Potentials to maximize cortical activation and minimize artifacts

S Casarotto, M Fecchio, M Rosanova, G Varone… - Journal of Neuroscience …, 2022 - Elsevier
Background The impact of transcranial magnetic stimulation (TMS) on cortical neurons is
currently hard to predict based on a priori biophysical and anatomical knowledge alone. Lack …

[HTML][HTML] TAAC-TMS Adaptable Auditory Control: A universal tool to mask TMS clicks

…, A Astolfi, M Massimini, M Rosanova, M Fecchio - Journal of neuroscience …, 2022 - Elsevier
Background Coupling transcranial magnetic stimulation with electroencephalography (TMS-EEG)
allows recording the EEG response to a direct, non-invasive cortical perturbation. …

Local sleep-like cortical reactivity in the awake brain after focal injury

S Sarasso, S D'Ambrosio, M Fecchio, S Casarotto… - Brain, 2020 - academic.oup.com
The functional consequences of focal brain injury are thought to be contingent on neuronal
alterations extending beyond the area of structural damage. This phenomenon, also known …

Beyond alpha power: EEG spatial and spectral gradients robustly stratify disorders of consciousness

…, A Mazza, PD Trimarchi, M Boly, M Fecchio… - Cerebral …, 2023 - academic.oup.com
Neurophysiological markers can overcome the limitations of behavioural assessments of
Disorders of Consciousness (DoC). EEG alpha power emerged as a promising marker for DoC, …