User profiles for Matteo Pellegrini
matteo pellegriniuniversity of california Los Angeles Verified email at mcdb.ucla.edu Cited by 44705 |
Assigning protein functions by comparative genome analysis: protein phylogenetic profiles
M Pellegrini, EM Marcotte… - Proceedings of the …, 1999 - National Acad Sciences
Determining protein functions from genomic sequences is a central goal of bioinformatics.
We present a method based on the assumption that proteins that function together in a …
We present a method based on the assumption that proteins that function together in a …
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
Cytosine DNA methylation is important in regulating gene expression and in silencing
transposons and other repetitive sequences 1 , 2 . Recent genomic studies in Arabidopsis …
transposons and other repetitive sequences 1 , 2 . Recent genomic studies in Arabidopsis …
Conservation and divergence of methylation patterning in plants and animals
Cytosine DNA methylation is a heritable epigenetic mark present in many eukaryotic organisms.
Although DNA methylation likely has a conserved role in gene silencing, the levels and …
Although DNA methylation likely has a conserved role in gene silencing, the levels and …
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
…, W Dean, S Feng, SJ Cokus, S Andrews, M Pellegrini… - Nature, 2010 - nature.com
Epigenetic reprogramming including demethylation of DNA occurs in mammalian primordial
germ cells (PGCs) and in early embryos, and is important for the erasure of imprints and …
germ cells (PGCs) and in early embryos, and is important for the erasure of imprints and …
[HTML][HTML] Whole-Genome Analysis of Histone H3 Lysine 27 Trimethylation in Arabidopsis
…, S Cokus, YV Bernatavichute, M Pellegrini… - PLoS …, 2007 - journals.plos.org
Trimethylation of histone H3 lysine 27 (H3K27me3) plays critical roles in regulating animal
development, and in several cases, H3K27me3 is also required for the proper expression of …
development, and in several cases, H3K27me3 is also required for the proper expression of …
Detecting protein function and protein-protein interactions from genome sequences
A computational method is proposed for inferring protein interactions from genome sequences
on the basis of the observation that some pairs of interacting proteins have homologs in …
on the basis of the observation that some pairs of interacting proteins have homologs in …
[HTML][HTML] Genome-wide high-resolution mapping and functional analysis of DNA methylation in Arabidopsis
…, H Chen, IR Henderson, P Shinn, M Pellegrini… - Cell, 2006 - cell.com
Cytosine methylation is important for transposon silencing and epigenetic regulation of
endogenous genes, although the extent to which this DNA modification functions to regulate the …
endogenous genes, although the extent to which this DNA modification functions to regulate the …
A combined algorithm for genome-wide prediction of protein function
The availability of over 20 fully sequenced genomes has driven the development of new
methods to find protein function and interactions. Here we group proteins by correlated …
methods to find protein function and interactions. Here we group proteins by correlated …
[PDF][PDF] Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming
Pioneer transcription factors (TFs) access silent chromatin and initiate cell-fate changes,
using diverse types of DNA binding domains (DBDs). FoxA, the paradigm pioneer TF, has a …
using diverse types of DNA binding domains (DBDs). FoxA, the paradigm pioneer TF, has a …
Relationship between nucleosome positioning and DNA methylation
Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of
approximately 147 bases of DNA wrapped around a histone octamer 1 , 2 . Here we report a …
approximately 147 bases of DNA wrapped around a histone octamer 1 , 2 . Here we report a …