Genomic analyses identify molecular subtypes of pancreatic cancer
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently
mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/…
mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/…
[PDF][PDF] Integrated proteogenomic characterization of clear cell renal cell carcinoma
…, MJ Domagalski, MA Gritsenko, M Anderson… - Cell, 2019 - cell.com
To elucidate the deregulated functional modules that drive clear cell renal cell carcinoma (ccRCC),
we performed comprehensive genomic, epigenomic, transcriptomic, proteomic, and …
we performed comprehensive genomic, epigenomic, transcriptomic, proteomic, and …
Whole genomes redefine the mutational landscape of pancreatic cancer
…, PJ Wilson, E Markham, N Cloonan, MJ Anderson… - Nature, 2015 - nature.com
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden.
We performed whole-genome sequencing and copy number variation (CNV) analysis of …
We performed whole-genome sequencing and copy number variation (CNV) analysis of …
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed
exome sequencing and copy number analysis to define genomic aberrations in a …
exome sequencing and copy number analysis to define genomic aberrations in a …
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
GM Denning, MP Anderson, JF Amara, J Marshall… - nature, 1992 - nature.com
CYSTIC fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane Cl −
channel regulated by cyclic AMP-dependent phosphorylation and by intracellular ATP 1–7 . …
channel regulated by cyclic AMP-dependent phosphorylation and by intracellular ATP 1–7 . …
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity
MP Anderson, RJ Gregory, S Thompson, DW Souza… - Science, 1991 - science.org
Expression of the cystic fibrosis transmembrane conductance regulator (CFTR) generates
adenosine 3′,5′-monophosphate (cAMP)-regulated chloride channels, indicating that …
adenosine 3′,5′-monophosphate (cAMP)-regulated chloride channels, indicating that …
Whole–genome characterization of chemoresistant ovarian cancer
Patients with high-grade serous ovarian cancer (HGSC) have experienced little
improvement in overall survival, and standard treatment has not advanced beyond platinum-based …
improvement in overall survival, and standard treatment has not advanced beyond platinum-based …
Whole-genome landscape of pancreatic neuroendocrine tumours
…, C Nourse, E Nourbakhsh, PJ Wilson, MJ Anderson… - Nature, 2017 - nature.com
The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to
more sensitive detection methods, and this increase is creating challenges for clinical …
more sensitive detection methods, and this increase is creating challenges for clinical …
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells
DP Rich, MP Anderson, RJ Gregory, SH Cheng, S Paul… - Nature, 1990 - nature.com
The cystic fibrosis transmembrane conductance regulator (CFTR) was expressed in cultured
cystic fibrosis airway epithelial cells and Cl − channel activation assessed in single cells …
cystic fibrosis airway epithelial cells and Cl − channel activation assessed in single cells …
[BOOK][B] The rise of modern diplomacy 1450-1919
MS Anderson - 2014 - taylorfrancis.com
Though international relations and the rise and fall of European states are widely studied,
little is available to students and non-specialists on the origins, development and operation of …
little is available to students and non-specialists on the origins, development and operation of …