We have used the patch-clamp electrical recording technique on giant spheroplasts of
Escherichia coli and have discovered pressure-activated ion channels. The channels have the …

The excretory cell extends a tubular process, or canal, along the basolateral surface of the
epidermis to form the nematode renal epithelium. This cell can undergo normal tubulogenesis …

The excretory system of the nematode Caenorhabditis elegans is a superb model of tubular
organogenesis involving a minimum of cells. The system consists of just three unicellular …

Many unicellular tubes such as capillaries form lumens intracellularly, a process that is not
well understood. Here we show that the cortical membrane organizer ERM-1 is required to …

The formation and regulation of tubule shape and size is fundamental to the development
and function of many tissues and organs in metazoan organisms. The excretory canals of the …

The exc mutations of Caenorhabditis elegans alter the position and shape of the apical
cytoskeleton in polarized epithelial cells. Mutants in exc-7 form small cysts throughout the tubular …

Maintenance of the shape of biological tubules is critical for development and physiology of
metazoan organisms. Loss of function of the Caenorhabditis elegans FGD protein EXC-5 …

The Caenorhabditis elegans excretory cell extends tubular processes, called canals, along
the basolateral surface of the epidermis. Mutations in the exc‐5 gene cause tubulocystic …

Background The founding member of the EMAP-like protein family is the Echinoderm
Microtubule-Associated Protein (EMAP), so-named for its abundance in sea urchin, starfish, and …

Walleye dermal sarcomas are associated with the presence of a complex retrovirus, walleye
dermal sarcoma virus (WDSV). These sarcomas develop and regress seasonally in …