Dopamine regulates reward, cognition, and locomotor functions. By mediating rapid reuptake
of extracellular dopamine, the dopamine transporter is critical for spatiotemporal control of …

A fundamental concept in neuroscience is the transmission of information between neurons
via neurotransmitters, -modulators, and -peptides. For the past decades, the gold standard …

The dorsal (DS) and ventral striatum (VS) receive dopaminergic projections that control
motor functions and reward-related behavior. It remains poorly understood how dopamine …

Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disease
characterized by the accumulation of aggregated amyloid beta (Aβ) and hyperphosphorylated …

Introduction Preterm infants have increased risk of impaired neurodevelopment to which
reduced systemic levels of insulin-like growth factor 1 (IGF-1) in the weeks after birth may play a …

BAR domains are dimeric protein modules that sense, induce, and stabilize lipid membrane
curvature. Here, we show that membrane curvature sensing (MCS) directs cellular …

There has been a marked increase in the availability of synthetic drugs designed to mimic
the effects of marijuana. These cannabimimetic drugs, sold illicitly as ‘Spice’ and related …

The nanoscopic organization and regulation of individual molecular components in presynaptic
varicosities of neurons releasing modulatory volume neurotransmitters like dopamine (…

Dysfunctional dopaminergic neurotransmission is central to movement disorders and mental
diseases. The dopamine transporter (DAT) regulates extracellular dopamine levels, but the …

Dual-color single-molecule localization microscopy (SMLM) provides unprecedented possibilities
for detailed studies of colocalization of different molecular species in a cell. However, …