Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear …

M Hardwick, D Fertikh, M Culty, H Li, B Vidic… - Cancer research, 1999 - AACR
Aberrant cell proliferation and increased invasive and metastatic behavior are hallmarks of
the advancement of breast cancer. Numerous studies implicate a role for cholesterol in the …

In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding

F Delavoie, H Li, M Hardwick, JC Robert… - Biochemistry, 2003 - ACS Publications
Peripheral-type benzodiazepine receptor (PBR) is an 18 kDa high-affinity drug ligand and
cholesterol binding protein involved in various cell functions. Antisera for distinct PBR areas …

[PDF][PDF] Comparison of protection against ocular contamination with disposable eyewear products

…, M Cotton, M Hardwick - … Hospital Center Study …, 2020 - medonyx.com
Background: Current CDC recommendations for medical first responders call for use of
disposable N95 respirator and eye protection (eg, goggles; eye shield) when coming into close …

Zinc-embedded polyamide fabrics inactivate SARS-CoV-2 and influenza A virus

…, JY Siegers, W Yung, M Hardwick… - … applied materials & …, 2021 - ACS Publications
Influenza A viruses (IAV) and SARS-CoV-2 can spread via liquid droplets and aerosols. Face
masks and other personal protective equipment (PPE) can act as barriers that prevent the …

Therapy for naming difficulties in bilingual aphasia: which language benefits?

…, J Marshall, T Pring, M Hardwick - International Journal of …, 2011 - Wiley Online Library
Background: The majority of the world's population is bilingual. Yet, therapy studies involving
bilingual people with aphasia are rare and have produced conflicting results. One recent …

Drug-induced inhibition of the peripheral-type benzodiazepine receptor expression and cell proliferation in human breast cancer cells.

…, A Kapsis, H Li, H Amri, M Hardwick… - Anticancer …, 2000 - europepmc.org
The peripheral-type benzodiazepine receptor (PBR) expression and localization correlate
with human breast cancer cell proliferation and aggressive phenotype expression. The …

[PDF][PDF] Potential use of runoff attenuation features in small rural catchments for flood mitigation

…, G Owen, J Jonczyk, N Barber, M Hardwick… - … (ed) Newcastle upon …, 2013 - ydrt.org.uk
Following a number of recent severe flood events across the North East of England, the
Environment Agency (EA) have been working with Newcastle University (NU) to develop a …

Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation

W Li, MJ Hardwick, D Rosenthal, M Culty… - biochemical …, 2007 - Elsevier
The peripheral-type benzodiazepine receptor (PBR), an 18-kDa high affinity drug and
cholesterol binding protein, is expressed at high levels in various cancers. Its expression is …

Peripheral-type benzodiazepine receptor (PBR) gene amplification in MDA-MB-231 aggressive breast cancer cells

M Hardwick, LR Cavalli, KD Barlow, BR Haddad… - Cancer genetics and …, 2002 - Elsevier
Recent studies using human breast cancer cell lines, animal models, and human tissue
biopsies have suggested a close correlation between the expression of the peripheral-type …

In vivo imaging of peripheral benzodiazepine receptors in mouse lungs: a biomarker of inflammation

MJ Hardwick, MK Chen, K Baidoo… - Molecular …, 2005 - journals.sagepub.com
The ability to visualize the immune response with radioligands targeted to immune cells will
enhance our understanding of cellular responses in inflammatory diseases. Peripheral …