Neutrophils are essential for host defence and are recruited to sites of inflammation in
response to tissue injury or infection. For inflammation to resolve, these cells must be cleared …

There remains a need to identify novel pro-resolution drugs for treatment of inflammatory
disease. To date, there are no neutrophil-specific anti-inflammatory treatments in clinical use, …

During inflammation, dysregulated neutrophil behaviour can play a major role in a range of
chronic inflammatory diseases, for many of which current treatments are generally ineffective. …

The growing world population and global increases in the standard of living both result in
an increasing demand for food, feed and other plant‐derived products. In the coming years, …

Wheat provides 20% of calories and protein consumed by humans. Recent genetic gains
are <1% per annum (pa), insufficient to meet future demand. The Wheat Yield Consortium …

A substantial increase in grain yield potential is required, along with better use of water and
fertilizer, to ensure food security and environmental protection in future decades. For …

Recent advances in crop research have the potential to accelerate genetic gains in wheat,
especially if co-ordinated with a breeding perspective. For example, improving …

Importance Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …

Background The efficacy of interleukin-6 receptor blockade in hospitalized patients with
coronavirus disease 2019 (Covid-19) who are not receiving mechanical ventilation is unclear. …

Martin Hasselblatt· Inga Nagel· Florian Oyen· Kerstin Bartelheim· Robert B. Russell· Ulrich
Schüller· Reimar Junckerstorff· Marc Rosenblum· Ali H. Alassiri· Sabrina Rossi· Irene Schmid· …