User profiles for Matthew Jenner

Matthew Jenner

- Verified email at uhs.nhs.uk - Cited by 4925

Matthew Jenner

- Verified email at warwick.ac.uk - Cited by 1051

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value

…, L Chiecchio, NJ Dickens, MW Jenner… - Blood, The Journal …, 2010 - ashpublications.org
To obtain a comprehensive genomic profile of presenting multiple myeloma cases we
performed high-resolution single nucleotide polymorphism mapping array analysis in 114 …

[HTML][HTML] Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised …

…, K Karunanithi, J Lindsay, MW Jenner… - The Lancet …, 2019 - thelancet.com
Background Patients with multiple myeloma treated with lenalidomide maintenance therapy
have improved progression-free survival, primarily following autologous stem-cell …

Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a …

…, M Janakiram, I Jaiyesimi, M Jenner… - The Lancet …, 2019 - thelancet.com
Background As lenalidomide becomes increasingly established for upfront treatment of
multiple myeloma, patients refractory to this drug represent a population with an unmet need. …

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

BA Walker, PE Leone, MW Jenner, C Li, D Gonzalez… - Blood, 2006 - ashpublications.org
Multiple myeloma is characterized by genomic alterations frequently involving gains and
losses of chromosomes. Single nucleotide polymorphism (SNP)-based mapping arrays allow …

[HTML][HTML] Real‐world assessment of the clinical impact of symptomatic infection with severe acute respiratory syndrome coronavirus (COVID‐19 disease) in patients …

…, K Ramasamy, M Kaiser, M Jenner… - British journal of …, 2020 - ncbi.nlm.nih.gov
3. Cavalli G, De Luca G, Campochiaro C, Della-Torre E, Ripa M, Canetti D, et al. Interleukin-1
blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress …

Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome

…, DC Johnson, JL Brito, A Zeisig, MW Jenner… - Clinical Cancer …, 2010 - AACR
Purpose: Myeloma is a clonal malignancy of plasma cells. Poor-prognosis risk is currently
identified by clinical and cytogenetic features. However, these indicators do not capture all …

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple …

MW Jenner, PE Leone, BA Walker… - Blood, The Journal …, 2007 - ashpublications.org
We performed fluorescent in situ hybridization (FISH) for 16q23 abnormalities in 861 patients
with newly diagnosed multiple myeloma and identified deletion of 16q [del(16q)] in 19.5%. …

Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria

AJ Mullins, JAH Murray, MJ Bull, M Jenner… - Nature …, 2019 - nature.com
Beneficial microorganisms are widely used in agriculture for control of plant pathogens, but
a lack of efficacy and safety information has limited the exploitation of multiple promising …

[HTML][HTML] MMSET deregulation affects cell cycle progression and adhesion regulons in t (4; 14) myeloma plasma cells

JLR Brito, B Walker, M Jenner, NJ Dickens… - …, 2009 - ncbi.nlm.nih.gov
Background The recurrent immunoglobulin translocation, t (4; 14)(p16; q32) occurs in 15%
of multiple myeloma patients and is associated with poor prognosis, through an unknown …

Deletions of CDKN2C in Multiple Myeloma: Biological and Clinical Implications

PE Leone, BA Walker, MW Jenner, L Chiecchio… - Clinical Cancer …, 2008 - AACR
Purpose: Deletions of chromosome 1 have been described in 7% to 40% of cases of
myeloma with inconsistent clinical consequences. CDKN2C at 1p32.3 has been identified in …