User profiles for Matthew MacKay

Matthew MacKay

- Verified email at med.cornell.edu - Cited by 4554

Matthew MacKay

- Verified email at stanford.edu - Cited by 230

Self-tuning networks: Bilevel optimization of hyperparameters using structured best-response functions

M MacKay, P Vicol, J Lorraine, D Duvenaud… - arXiv preprint arXiv …, 2019 - arxiv.org
Hyperparameter optimization can be formulated as a bilevel optimization problem, where
the optimal parameters on the training set depend on the hyperparameters. We aim to adapt …

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

…, G Minuesa, T Chou, A Chow, Y Saletore, M MacKay… - Nature medicine, 2017 - nature.com
N 6 -methyladenosine (m 6 A) is an abundant nucleotide modification in mRNA that is
required for the differentiation of mouse embryonic stem cells. However, it remains unknown …

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

…, SS Laurie, B Lee-McMullen, SB Lumpkins, M MacKay… - Science, 2019 - science.org
INTRODUCTION To date, 559 humans have been flown into space, but long-duration (>300
days) missions are rare (n = 8 total). Long-duration missions that will take humans to Mars …

Active-vision for the autonomous surveillance of dynamic, multi-object environments

A Bakhtari, M Mackay, B Benhabib - Journal of Intelligent and Robotic …, 2009 - Springer
This paper presents a novel method for active-vision-based sensing-system reconfiguration
for the autonomous surveillance of an object-of-interest as it travels through a multi-object …

[HTML][HTML] Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated persons

…, J Metti, G Khullar, R Baits, M MacKay… - … England Journal of …, 2021 - Mass Medical Soc
Viral Dynamics of SARS-CoV-2 Variants in Vaccinated and Unvaccinated Persons | NEJM
Skip to main content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn …

[HTML][HTML] Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2

…, G Khullar, J Metti, JT Dudley, MJ MacKay… - PLoS …, 2021 - journals.plos.org
With the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
variants that may increase transmissibility and/or cause escape from immune responses, …

[PDF][PDF] Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration

E Afshinnekoo, RT Scott, MJ MacKay, E Pariset… - Cell, 2020 - cell.com
Research on astronaut health and model organisms have revealed six features of spaceflight
biology that guide our current understanding of fundamental molecular changes that occur …

[HTML][HTML] Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug …

…, A Shaiber, D Danko, E Afshinnekoo, M MacKay… - Nature …, 2021 - nature.com
In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
killed over a million people, including >25,000 in New York City (NYC) alone. The …

Viral dynamics and duration of PCR positivity of the SARS-CoV-2 Omicron variant

…, S Connelly, DJ Anderson, G Khullar, M MacKay… - MedRxiv, 2022 - medrxiv.org
Background The Omicron SARS-CoV-2 variant is responsible for a major wave of COVID-19,
with record case counts reflecting high transmissibility and escape from prior immunity. …

[PDF][PDF] Early introductions and transmission of SARS-CoV-2 variant B. 1.1. 7 in the United States

…, J Rothman, AL Valesano, MJ MacKay… - Cell, 2021 - cell.com
The emergence and spread of SARS-CoV-2 lineage B.1.1.7, first detected in the United
Kingdom, has become a global public health concern because of its increased transmissibility. …