The epitopes defined by HIV-1 broadly neutralizing antibodies (bNAbs) are valuable templates
for vaccine design, and studies of the immunological development of these antibodies …

Computational neutralization fingerprinting, NFP, is an efficient and accurate method for
predicting the epitope specificities of polyclonal antibody responses to HIV-1 infection. Here, we …

Increasing drug resistance and the lack of an effective vaccine are the main factors contributing
to Mycobacterium tuberculosis (Mtb) being a major cause of death globally. Despite …

One of the goals of HIV-1 vaccine development is the elicitation of neutralizing antibodies
against vulnerable regions on the envelope glycoprotein (Env) viral spike. Broadly neutralizing …

Alphaviruses are RNA viruses that represent emerging public health threats. To identify
protective antibodies, we immunized macaques with a mixture of western, eastern, and …

We manipulated SIVmac239Δnef, a model of major histocompatibility complex (MHC)-independent
viral control, to evaluate characteristics of effective cellular responses mounted by …

Few studies have evaluated the impact of the viral challenge route on protection against a
heterologous simian immunodeficiency virus (SIV) challenge. We vaccinated seven …

Understanding the immunological control of pathogens requires a detailed evaluation of the
mechanistic contributions of individual cell types within the immune system. While knockout …

We evaluated the contribution of CD8αβ + T cells to control of live-attenuated simian
immunodeficiency virus (LASIV) replication during chronic infection and subsequent protection from …

… by the seizure and intelligence arms of enforcement agencies, surveys of drug use attitudes,
knowledge and experience, surveys of known users and surveys of hidden users (Sutton & …