User profiles for Matthew Semler

Matthew W. Semler

Vanderbilt University Medical Center
Verified email at vanderbilt.edu
Cited by 10651

[HTML][HTML] Video versus direct laryngoscopy for tracheal intubation of critically ill adults

…, AA Ginde, JD Casey, MW Semler - … England Journal of …, 2023 - Mass Medical Soc
Background Whether video laryngoscopy as compared with direct laryngoscopy increases
the likelihood of successful tracheal intubation on the first attempt among critically ill adults is …

[HTML][HTML] Balanced crystalloids versus saline in critically ill adults

MW Semler, WH Self, JP Wanderer… - … England Journal of …, 2018 - Mass Medical Soc
Background Both balanced crystalloids and saline are used for intravenous fluid administration
in critically ill adults, but it is not known which results in better clinical outcomes. Methods …

Factors associated with death in critically ill patients with coronavirus disease 2019 in the US

…, HB Gershengorn, MA Hernán, MW Semler… - JAMA internal …, 2020 - jamanetwork.com
Importance The US is currently an epicenter of the coronavirus disease 2019 (COVID-19)
pandemic, yet few national data are available on patient characteristics, treatment, and …

Association between early treatment with tocilizumab and mortality among critically ill patients with COVID-19

…, HB Gershengorn, DJ Douin, MW Semler… - JAMA internal …, 2021 - jamanetwork.com
Importance Therapies that improve survival in critically ill patients with coronavirus disease
2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 …

Effect of hydroxychloroquine on clinical status at 14 days in hospitalized patients with COVID-19: a randomized clinical trial

WH Self, MW Semler, LM Leither, JD Casey, DC Angus… - Jama, 2020 - jamanetwork.com
Importance Data on the efficacy of hydroxychloroquine for the treatment of coronavirus disease
2019 (COVID-19) are needed. Objective To determine whether hydroxychloroquine is an …

[HTML][HTML] Balanced crystalloids versus saline in noncritically ill adults

WH Self, MW Semler, JP Wanderer… - … England Journal of …, 2018 - Mass Medical Soc
Background Comparative clinical effects of balanced crystalloids and saline are uncertain,
particularly in noncritically ill patients cared for outside an intensive care unit (ICU). Methods …

[HTML][HTML] Oxygen-saturation targets for critically ill adults receiving mechanical ventilation

MW Semler, JD Casey, BD Lloyd… - … England Journal of …, 2022 - Mass Medical Soc
Background Invasive mechanical ventilation in critically ill adults involves adjusting the
fraction of inspired oxygen to maintain arterial oxygen saturation. The oxygen-saturation target …

Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial

B Andrews, MW Semler, L Muchemwa, P Kelly, S Lakhi… - Jama, 2017 - jamanetwork.com
Importance The effect of an early resuscitation protocol on sepsis outcomes in developing
countries remains unknown. Objective To determine whether an early resuscitation protocol …

Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS

…, T Koyama, JA Bastarache, CM Shaver, MW Semler… - Thorax, 2018 - thorax.bmj.com
Background There is no accurate, non-invasive measurement to estimate the degree of
pulmonary oedema in acute respiratory distress syndrome (ARDS). We developed the …

[HTML][HTML] Extracorporeal membrane oxygenation in patients with severe respiratory failure from COVID-19

…, T Shaukat, H Singh, AJ Admon, MW Semler… - Intensive care …, 2021 - Springer
Purpose Limited data are available on venovenous extracorporeal membrane oxygenation (ECMO)
in patients with severe hypoxemic respiratory failure from coronavirus disease 2019 (…