Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Gene expression is central to the genotype-phenotype relationship in all organisms, and it
is an important component of the genetic basis for evolutionary change in diverse aspects of …

The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from
the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and …

We present CAFE (Computational Analysis of gene Family Evolution), a tool for the statistical
analysis of the evolution of the size of gene families. It uses a stochastic birth and death …

… Even with isogamy, however, mating is often not random but requires that joining cells differ
at a mating type (MAT) locus. Mating types might have evolved to orchestrate the developmental …

The metaphor of ‘genomic islands of speciation’ was first used to describe heterogeneous
differentiation among loci between the genomes of closely related species. The biological …

Sequencing of multiple related species followed by comparative genomics analysis constitutes
a powerful approach for the systematic understanding of any genome. Here, we use the …

The African malaria mosquito, Anopheles gambiae sensu stricto (A. gambiae), provides a
unique opportunity to study the evolution of reproductive isolation because it is divided into two …

The population genetic perspective is that the processes shaping genomic variation can be
revealed only through simultaneous investigation of sequence polymorphism and …

Most proteins do not evolve in isolation, but as components of complex genetic networks.
Therefore, a protein's position in a network may indicate how central it is to cellular function and…