[HTML][HTML] Identification of nine new susceptibility loci for endometrial cancer
…, HA Risch, PAW Rogers, M Rübner… - Nature …, 2018 - nature.com
Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract
in developed countries. Through genome-wide association studies (GWAS), we have …
in developed countries. Through genome-wide association studies (GWAS), we have …
[HTML][HTML] MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer
Breast cancer is a heterogeneous disease with distinct molecular subtypes including the
aggressive subtype triple-negative breast cancer (TNBC). We compared blood-borne miRNA …
aggressive subtype triple-negative breast cancer (TNBC). We compared blood-borne miRNA …
[HTML][HTML] BRCA1/2 mutations and bevacizumab in the neoadjuvant treatment of breast cancer: response and prognosis results in patients with triple-negative breast …
…, KE Weber, B Rack, M Rübner… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Purpose BRCA1/2 mutations are frequent in patients with triple-negative breast cancer (TNBC).
These patients are often treated with primary systemic chemotherapy. The aim of this …
These patients are often treated with primary systemic chemotherapy. The aim of this …
[HTML][HTML] Mutations in BRCA1/2 and other panel genes in patients with metastatic breast cancer—Association with patient and disease characteristics and effect on …
…, L Häberle, SN Hart, M Rübner… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
PURPOSE Among patients with metastatic breast cancer (mBC), the frequency of germline
mutations in cancer susceptibility genes and the clinical relevance of these mutations are …
mutations in cancer susceptibility genes and the clinical relevance of these mutations are …
Genetic risk score Mendelian randomization shows that obesity measured as body mass index, but not waist: hip ratio, is causal for endometrial cancer
…, AB Ekici, PA Fasching, A Hein, M Rübner… - … , biomarkers & prevention, 2016 - AACR
Background: The strongest known risk factor for endometrial cancer is obesity. To determine
whether SNPs associated with increased body mass index (BMI) or waist–hip ratio (WHR) …
whether SNPs associated with increased body mass index (BMI) or waist–hip ratio (WHR) …
Genetic overlap between endometriosis and endometrial cancer: evidence from cross‐disease genetic correlation and GWAS meta‐analyses
…, MW Beckmann, AB Ekici, A Hein, M Rübner… - Cancer …, 2018 - Wiley Online Library
Epidemiological, biological, and molecular data suggest links between endometriosis and
endometrial cancer, with recent epidemiological studies providing evidence for an association …
endometrial cancer, with recent epidemiological studies providing evidence for an association …
Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer
…, SP Renner, HA Risch, M Rübner… - … journal of cancer, 2021 - Wiley Online Library
Blood lipids have been associated with the development of a range of cancers, including
breast, lung and colorectal cancer. For endometrial cancer, observational studies have …
breast, lung and colorectal cancer. For endometrial cancer, observational studies have …
Aluminium–aluminium compound fabrication by high pressure die casting
M Rübner, M Günzl, C Körner, RF Singer - Materials Science and …, 2011 - Elsevier
This study examines the development of aluminium–aluminium compounds during high
pressure die casting. An aluminium insert was mounted into a die casting mould and embedded …
pressure die casting. An aluminium insert was mounted into a die casting mould and embedded …
TILGen: a program to investigate immune targets in breast cancer patients-first results on the influence of tumor-infiltrating lymphocytes
…, MW Beckmann, A Hartmann, PA Fasching, M Rübner - Breast Care, 2018 - karger.com
Background: Despite advancements in the treatment of primary and metastatic breast cancer,
many patients lack a durable response to these treatments. Patients with triplenegative …
many patients lack a durable response to these treatments. Patients with triplenegative …
[HTML][HTML] Pembrolizumab in combination with nab-paclitaxel for the treatment of patients with early-stage triple-negative breast cancer–A single-arm phase II trial …
…, HC Kolberg, L Häberle, S Uhrig, M Rübner… - European Journal of …, 2023 - Elsevier
Background Pembrolizumab is approved for the neoadjuvant/adjuvant treatment of early
triple-negative breast cancer (TNBC) patients in combination with chemotherapy. The Keynote-…
triple-negative breast cancer (TNBC) patients in combination with chemotherapy. The Keynote-…