User profiles for Matthias Steinrücken
Matthias SteinrueckenUniversity of Chicago, Department of Ecology & Evolution Verified email at uchicago.edu Cited by 2086 |
Genomic evidence for the Pleistocene and recent population history of Native Americans
INTRODUCTION The consensus view on the peopling of the Americas is that ancestors of
modern Native Americans entered the Americas from Siberia via the Bering Land Bridge and …
modern Native Americans entered the Americas from Siberia via the Bering Land Bridge and …
[HTML][HTML] Evolution of immune genes is associated with the Black Death
…, D Missiakas, GA Rouleau, M Steinrücken… - Nature, 2022 - nature.com
Infectious diseases are among the strongest selective pressures driving human evolution 1 ,
2 . This includes the single greatest mortality event in recorded history, the first outbreak of …
2 . This includes the single greatest mortality event in recorded history, the first outbreak of …
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Despite broad agreement that the Americas were initially populated via Beringia, the land
bridge that connected far northeast Asia with northwestern North America during the …
bridge that connected far northeast Asia with northwestern North America during the …
[PDF][PDF] Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders
…, E Benito, Q Zhu, C Lee, F Antonacci, M Steinrücken… - Cell, 2022 - cell.com
Unlike copy number variants (CNVs), inversions remain an underexplored genetic variation
class. By integrating multiple genomic technologies, we discover 729 inversions in 41 …
class. By integrating multiple genomic technologies, we discover 729 inversions in 41 …
[HTML][HTML] Parental relatedness through time revealed by runs of homozygosity in ancient DNA
Parental relatedness of present-day humans varies substantially across the globe, but little
is known about the past. Here we analyze ancient DNA, leveraging that parental relatedness …
is known about the past. Here we analyze ancient DNA, leveraging that parental relatedness …
Inference of complex population histories using whole-genome sequences from multiple populations
There has been much interest in analyzing genome-scale DNA sequence data to infer
population histories, but inference methods developed hitherto are limited in model complexity …
population histories, but inference methods developed hitherto are limited in model complexity …
Model‐based detection and analysis of introgressed Neanderthal ancestry in modern humans
Genetic evidence has revealed that the ancestors of modern human populations outside Africa
and their hominin sister groups, notably Neanderthals, exchanged genetic material in the …
and their hominin sister groups, notably Neanderthals, exchanged genetic material in the …
A simple method for finding explicit analytic transition densities of diffusion processes with general diploid selection
YS Song, M Steinrücken - Genetics, 2012 - academic.oup.com
The transition density function of the Wright–Fisher diffusion describes the evolution of
population-wide allele frequencies over time. This function has important practical applications in …
population-wide allele frequencies over time. This function has important practical applications in …
A modified lookdown construction for the Xi-Fleming-Viot process with mutation and populations with recurrent bottlenecks
M Birkner, J Blath, M Möhle, M Steinrücken… - arXiv preprint arXiv …, 2008 - arxiv.org
Let $\Lambda$ be a finite measure on the unit interval. A $\Lambda$-Fleming-Viot process
is a probability measure valued Markov process which is dual to a coalescent with multiple …
is a probability measure valued Markov process which is dual to a coalescent with multiple …
Inference of population history using coalescent HMMs: review and outlook
Studying how diverse human populations are related is of historical and anthropological
interest, in addition to providing a realistic null model for testing for signatures of natural …
interest, in addition to providing a realistic null model for testing for signatures of natural …