BACKGROUND & AIMS: Interferon-based therapies for hepatitis C virus (HCV) infection are
limited by side effects and incomplete response rates, particularly among transplant …

Quercetin is a natural flavonoid, which has been shown to have anti hepatitis C virus (HCV)
properties. However, the exact mechanisms whereby quercetin impacts the HCV life cycle …

During hepatitis B virus (HBV) infection, HBV subviral particles (SVP) are produced in large
excess in comparison to infectious virions and account for the major source of HBV surface …

Aminoquinolines and piperazines, linked or not, have been used successfully to treat malaria,
and some molecules of this family also exhibit antiviral properties. Here we tested several …

Nucleic acid polymer (NAP) REP 2139 treatment was shown to block the release of viral
surface antigen in duck HBV (DHBV)‐infected ducks and in patients with chronic HBV or HBV/…

Objective HCV is intimately linked with the liver lipid metabolism, devoted to the efflux of
triacylglycerols stored in lipid droplets (LDs) in the form of triacylglycerol-rich very-low-density …

Hepatitis C virus (HCV) is a leading cause of liver diseases including the development of
hepatocellular carcinoma (HCC). Particularly, core protein has been involved in HCV-related …

In hepatitis C virus (HCV) polyprotein sequence, core protein terminates with E1 envelope
signal peptide. Cleavage by signal peptidase (SP) separates E1 from the complete form of …

L’infection par le virus de l’hépatite C (VHC) perturbe le métabolisme lipidique de son hôte.
En effet, les particules virales sont hétérogènes mais les plus infectieuses sont celles …

The liver-specific micro-RNA-122 (miR-122) is required for the replication of hepatitis C virus
(HCV). The direct interaction between miR-122 and the 5’ untranslated region of the HCV …