Inhomogeneous mechanotransduction defines the spatial pattern of apoptosis-induced compensatory proliferation

T Kawaue, I Yow, Y Pan, AP Le, Y Lou, M Loberas… - Developmental cell, 2023 - cell.com
The number of cells in tissues is controlled by cell division and cell death, and its misregulation
could lead to pathological conditions such as cancer. To maintain the cell numbers, a cell…

[HTML][HTML] Scalable mesenchymal stem cell enrichment from bone marrow aspirate using deterministic lateral displacement (DLD) microfluidic sorting

NTK Zen, KK Zeming, KL Teo, M Loberas, J Lee… - Lab on a Chip, 2023 - pubs.rsc.org
The growing interest in regenerative medicine has opened new avenues for novel cell
therapies using stem cells. Bone marrow aspirate (BMA) is an important source of stromal …

[HTML][HTML] A zinc-finger fusion protein refines Gal4-defined neural circuits

…, F Mohammad, JY Chua, JSW Lam, M Loberas… - Molecular Brain, 2018 - Springer
The analysis of behavior requires that the underlying neuronal circuits are identified and
genetically isolated. In several major model species—most notably Drosophila—…

Mechanics defines the spatial pattern of compensatory proliferation

T Kawaue, I Yow, AP Le, Y Lou, M Loberas, M Shagirov… - bioRxiv, 2021 - biorxiv.org
The number of cells in tissues is tightly controlled by cell division and cell death, and misregulation
of cell numbers could lead to pathological conditions such as cancer. To maintain cell …

Scalable Mesenchymal Stem Cells Enrichment from Bone Marrow Aspirate using Deterministic Lateral Displacement (DLD) Microfluidics Sorting

N Tan, KZ Kwek, KL Teo, M Loberas, JL Lee, CR Goh… - bioRxiv, 2023 - biorxiv.org
The growing interest in regenerative medicine has opened new avenues for novel cell
therapies using stem cells. Bone Marrow Aspirate (BMA) is an important source of stromal …

Induced pluripotent stem cells-derived craniofacial mesenchymal progenitor cells

A Srinivasan, M Loberas, YC Toh, JH Hui - iPSC Derived Progenitors, 2022 - Elsevier
The neural crest is a multipotent stem cell population in the developing embryo that plays
an important role in the development of the craniofacial region. Craniofacial-specific …

Bone Marrow Aspirate Concentrate for the Treatment of Early Osteoarthritis

A Srinivasan, M Loberas, JH Hui - Early Osteoarthritis: State-of-the-Art …, 2022 - Springer
Bone marrow aspirate concentrate (BMAC) is one of the emerging orthobiologics that have
shown promise for the treatment of early osteoarthritis (OA). Autologous BMAC can be easily …

The cellular and molecular origins of beak morphology

RA Schneider, JA Helms - Science, 2003 - science.org
Cellular and molecular mechanisms underlying differences in beak morphology likely
involve interactions among multiple embryonic populations. We exchanged neural crest cells …

Early Osteoarthritis

Part I “Early Osteoarthritis Definition, Epidemiology and Risk” is dedicated to methods for
early detection as well as epidemiological and economic aspects of the disease process in …

Apoptotic Force and Tissue Dynamics During Drosophila Embryogenesis

Y Toyama, XG Peralta, AR Wells, DP Kiehart… - Science, 2008 - science.org
Understanding cell morphogenesis during metazoan development requires knowledge of
how cells and the extracellular matrix produce and respond to forces. We investigated how …