Cell-density-dependent gene regulation by quorum-sensing systems has a crucial function
in bacterial physiology and pathogenesis. We demonstrate here that the Staphylococcus …

Biofilms are surface-attached agglomerations of microorganisms embedded in an extracellular
matrix. Biofilm-associated infections are difficult to eradicate and represent a significant …

We previously demonstrated that Streptococcus mutans expresses a functional agmatine
deiminase system (AgDS) encoded by the agmatine-inducible aguBDAC operon (AR Griswold, …

In Gram‐negative bacteria, thiol oxidoreductases catalyse the formation of disulphide bonds
(DSB) in extracytoplasmic proteins. In this study, we sought to identify DSB‐forming proteins …

Donor T-cell mediated graft versus host (GVH) effects may result from the aggregate alloreactivity
to minor histocompatibility antigens (mHA) presented by the human leukocyte antigen (…

Immune reconstitution kinetics and subsequent clinical outcomes in HLA-matched
recipients of allogeneic stem cell transplantation (SCT) are variable and difficult to predict. …

Whole exome sequencing ( WES ) was performed on stem cell transplant donor‐recipient (
D ‐ R ) pairs to determine the extent of potential antigenic variation at a molecular level. In a …

The extracytoplasmic assembly of the Dot/Icm type IVb secretion system (T4SS) of Legionella
pneumophila is dependent on correct disulfide bond (DSB) formation catalyzed by a novel …

Quantitative relationship between the magnitude of variation in minor histocompatibility
antigens (mHA) and graft versus host disease (GVHD) pathophysiology in stem cell transplant (…

Ipilimumab with and without anti–Programmed Death 1 (PD-1) improved overall survival (OS)
in melanoma. Despite this, the optimal dose and therapeutic mechanism of ipilimumab in …