User profiles for Max Wendell

Max Wendell

Emulate, Inc.
Verified email at emulatebio.com

Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications

…, W Tien-Street, DR Trinidad, J Velez, M Wendell… - Biorxiv, 2021 - biorxiv.org
… C max for each drug based on free (non-protein bound) drug concentrations, with the highest
concentrations at 300x C max … multiples of the free human C max compared to each of their …

[HTML][HTML] Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology

…, DR Trinidad, J Velez, M Wendell… - Communications …, 2022 - nature.com
… The drug dosing concentrations were determined from the unbound human C max of … max
(Supplementary Data 1). For each cycle, concentrations ranged from 0.1 to 1000 times C max

Engineering an Integrated Microphysiological System for Modeling Human Fibrotic Disease

MD Wendell - 2021 - search.proquest.com
Fibrotic diseases comprise up to 45% of deaths in the industrialized world. Few effective anti-fibrotic
therapeutics exist, due in part to the lack of human-relevant preclinical models. The …

Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology

…, DR Trinidad, J Velez, M Wendell… - Communications …, 2023 - nature.com
There was a mistake in Table 5 of this article. The specificity (%) value in the final row of
Table 5 (the ‘Spheroid’row) read ‘100’, but should have read ‘67’. There was also a …

Adaptable Fabrication of Vascularized Milliscale Tissues in Membrane-Free Organ Chips Manufactured with 3D Printed Molds

…, GW Kpeli, EA Olsen, W Bralower, CC Culp, M Wendell… - bioRxiv, 2023 - biorxiv.org
Inexpensive stereolithography (SLA) 3D printing enables rapid prototyping of resin molds
for polydimethylsiloxane (PDMS) soft lithography and organ chip fabrication, but geometric …

The tolerance approach to sensitivity analysis in linear programming

RE Wendell - Management Science, 1985 - pubsonline.informs.org
… One of the objectives of this paper is to characterize a maximum tolerance p"‘ for right-hand
side perturbations in that p is an allowable tolerance iff p < p*. By defining the tolerance …

Using bounds on the data in linear programming: The tolerance approach to sensitivity analysis

RE Wendell - Mathematical Programming, 1984 - Springer
… 1r To characterize the largest allowable tolerance we define the maximum tolerance of the
right-hand-side terms p* as the supremum of the allowable tolerances, that is, p* --- sup{p: p …

Tolerance sensitivity and optimality bounds in linear programming

RE Wendell - Management Science, 2004 - pubsonline.informs.org
… Herein, as partially previewed without proofs in Wendell (1997), we consider an approach
that characterizes the potential loss of optimality in terms of a maximum-regret function. We …

Approaches to sensitivity analysis in linear programming

JE Ward, RE Wendell - Annals of Operations Research, 1990 - Springer
… interpreted as finding the maximum percentage, called the maximum tolerance percentage,
by … consider the maximum that this difference can become. That is, following Wendell [46] let …

On efficient solutions to multiple objective mathematical programs

…, JF Thisse, JE Ward, RE Wendell - Management …, 1984 - pubsonline.informs.org
… In particular, a point is a quasi-efficient solution to a multiple objective mathematical
program if and only if it is an optimal solution to a scalar maximum problem for some set of …