Information on unique and coordinated regulation of transcription and translation in response
to stress is central to the understanding of cellular homeostasis. Here we used ribosome …

Bats account for one-fifth of mammalian species, are the only mammals with powered flight,
and are among the few animals that echolocate. The insect-eating Brandt’s bat (Myotis …

Ribosome profiling and high-throughput sequencing provide unprecedented opportunities
for the analysis of mRNA translation. Using this novel method, several studies have …

COVID‐19 is an ongoing pandemic caused by the SARS‐CoV‐2 coronavirus that poses
one of the greatest challenges to public health in recent years. SARS‐CoV‐2 is known to …

Reduced methionine (Met) intake can extend lifespan of rodents; however, whether this
regimen represents a general strategy for regulating aging has been controversial. Here we …

Subterranean mammals spend their lives in dark, unventilated environments that are rich in
carbon dioxide and ammonia and low in oxygen. Many of these animals are also long-lived …

Ribosome profiling has emerged as a powerful method to assess global gene translation,
but methodological and analytical challenges often lead to inconsistencies across labs and …

Several pharmacological, dietary, and genetic interventions that increase mammalian
lifespan are known, but general principles of lifespan extension remain unclear. Here, we …

Protein synthesis represents a major metabolic activity of the cell. However, how it is affected
by aging and how this in turn impacts cell function remains largely unexplored. To address …

The naked mole-rat (NMR) is an exceptionally long-lived rodent that shows no increase of
mortality with age, defining it as a demographically non-aging mammal. Here, we perform …