Cancer stem cells (CSC) are believed to be involved in tumor evasion of classical antitumor
therapies and have thus become an attractive target for further improvement of anticancer …

Colorectal cancer (CRC) is one of the most common malignancies worldwide. In spite of
various attempts to ameliorate outcome by escalating treatment, significant improvement is …

Malignancy is fuelled by distinct subsets of stem-like cells which persist under treatment and
provoke drug-resistant recurrence. Eradication of these cancer stem cells has therefore …

Tumour neoantigens arising from cancer-specific mutations generate a molecular fingerprint
that has a definite specificity for cancer. Although this fingerprint perfectly discriminates …

Background A particular characteristic of non–small cell lung cancer is the composition of
the tumor microenvironment with a very high proportion of fibroblastic stromal cells (FSCs). …

Ovarian cancer (OC) is the most lethal gynecological malignancy, with platinum‐based
chemotherapy remaining the mainstay for adjuvant treatment after surgery. The lack of indication …

In cancer patients, the clinical response to checkpoint-based immunotherapy is associated
with the composition and functional quality of the host microbiome. While the relevance of the …

The tumor microenvironment harbors cancer-associated fibroblasts that function as major
modulators of cancer progression. Here, we assessed to which extent distinct cancer-…

Rationale: Continuous positive airway pressure (CPAP) is the standard treatment for the
obstructive sleep apnea syndrome (OSAS), but long-term adherence remains a challenge. In a …

Sleep apnea (SA) is a prevalent disorder diagnosed by polysomnography (PSG) based on
the number of apnea–hypopnea events per hour of sleep (apnea–hypopnea index, AHI). …