User profiles for Maximilian Stahl

Maximilian Stahl

Dana-Farber Cancer Institute, Harvard University
Verified email at dfci.harvard.edu
Cited by 2908

Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management

S Shimony, M Stahl, RM Stone - American Journal of …, 2023 - Wiley Online Library
Disease overview Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell
cancer characterized by unbridled proliferation of malignant marrow stem cells with …

Clinical and molecular predictors of response and survival following venetoclax therapy in relapsed/refractory AML

M Stahl, K Menghrajani, A Derkach, A Chan… - Blood …, 2021 - ashpublications.org
Azacitidine + venetoclax, decitabine + venetoclax, and low-dose cytarabine + venetoclax
are now standard treatments for newly diagnosed older or unfit patients with acute myeloid …

[PDF][PDF] Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia

…, JMB Pineda, WJ Kim, S Chen, J Bourcier, M Stahl… - Cancer Cell, 2023 - cell.com
Therapy resistance is a major challenge in the treatment of cancer. Here, we performed
CRISPR-Cas9 screens across a broad range of therapies used in acute myeloid leukemia to …

Consensus proposal for revised International Working Group 2023 response criteria for higher-risk myelodysplastic syndromes

…, U Platzbecker, JP Bewersdorf, M Stahl… - Blood, The Journal …, 2023 - ashpublications.org
Myelodysplastic syndromes/myelodysplastic neoplasms (MDS) are associated with variable
clinical presentations and outcomes. The initial response criteria developed by the …

Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort

M Stahl, M DeVeaux, P Montesinos, R Itzykson… - Blood …, 2018 - ashpublications.org
Although hypomethylating agents (HMAs) are frequently used in the frontline treatment of
older acute myeloid leukemia (AML) patients, little is known about their effectiveness in …

Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells

…, S Benbarche, B Liu, J Pangallo, S Chen, M Stahl… - Nature …, 2022 - nature.com
Many cancers carry recurrent, change-of-function mutations affecting RNA splicing factors.
Here, we describe a method to harness this abnormal splicing activity to drive splicing factor …

The use of immunosuppressive therapy in MDS: clinical outcomes and their predictors in a large international patient cohort

M Stahl, M DeVeaux, T De Witte, J Neukirchen… - Blood …, 2018 - ashpublications.org
Most studies of immunosuppressive therapy (IST) in myelodysplastic syndromes (MDS) are
limited by small numbers and their single-center nature, and report conflicting data regarding …

Differentiation syndrome in acute promyelocytic leukaemia

M Stahl, MS Tallman - British journal of haematology, 2019 - Wiley Online Library
Acute promyelocytic leukaemia differentiation syndrome (APL DS) is seen when patients
with APL are treated with all‐trans retinoic acid (ATRA) and/or arsenic trioxide (ATO). …

Immunotherapy in acute myeloid leukemia and myelodysplastic syndromes: The dawn of a new era?

Y Liu, JP Bewersdorf, M Stahl, AM Zeidan - Blood reviews, 2019 - Elsevier
Immunotherapy has revolutionized therapy in both solid and liquid malignancies. The ability
to cure acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) with an …

[HTML][HTML] Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a …

…, MM Patnaik, JP Bewersdorf, M Stahl… - The Lancet …, 2020 - thelancet.com
The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome
coronavirus 2 is a global public health crisis. Multiple observations indicate poorer post-infection …