The SKN‐1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms

…, JW Green, C Au, A Benedetto, MA Thompson… - Aging cell, 2017 - Wiley Online Library
In C. elegans, the skn‐1 gene encodes a transcription factor that resembles mammalian
Nrf2 and activates a detoxification response. skn‐1 promotes resistance to oxidative stress (Oxr) …

RNA polymerase III limits longevity downstream of TORC1

D Filer, MA Thompson, V Takhaveev, AJ Dobson… - Nature, 2017 - nature.com
Three distinct RNA polymerases transcribe different classes of genes in the eukaryotic
nucleus 1 . RNA polymerase (Pol) III is the essential, evolutionarily conserved enzyme that …

[HTML][HTML] Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation

EA De-Souza, MA Thompson, RC Taylor - Nature Aging, 2023 - nature.com
Animals rely on chemosensory cues to survive in pathogen-rich environments. In Caenorhabditis
elegans, pathogenic bacteria trigger aversive behaviors through neuronal perception …

Olfaction: an emerging regulator of longevity and metabolism

MA Thompson, EA De-Souza - Trends in Cell Biology, 2023 - cell.com
Ageing is a malleable process influenced by the environment. Recent research reveals that
neurons interact with peripheral organs to regulate metabolism and longevity by responding …

[HTML][HTML] Neuronal SKN-1B modulates nutritional signalling pathways and mitochondrial networks to control satiety

N Tataridas-Pallas, MA Thompson, A Howard… - PLoS …, 2021 - journals.plos.org
The feeling of hunger or satiety results from integration of the sensory nervous system with
other physiological and metabolic cues. This regulates food intake, maintains homeostasis …

Longevity by RNA polymerase III inhibition downstream of TORC1

D Filer, MA Thompson, V Takhaveev, AJ Dobson… - Nature, 2017 - kar.kent.ac.uk
Three distinct RNA polymerases (Pols) transcribe different classes of genes in the eukaryotic
nucleus1. Pol III is the essential, evolutionarily conserved enzyme that generates short, non-…

Making friends: amity in American foreign policy

M Thompson - 2015 - ora.ox.ac.uk
This thesis examines an important but understudied phenomenon in international politics:
the role of amity in foreign policy. The core research question is "how have American …

[BOOK][B] The 1967 Arab-Israeli war: origins and consequences

WR Louis, A Shlaim - 2012 - books.google.com
… We would also like to record our very special thanks to two of our graduate students, Noa
Schonmann and Maximillian Thompson, for the invaluable part they played in organizing the …

Maternal free fatty acid concentration during pregnancy is associated with newborn hypothalamic microstructure in humans

JM Rasmussen, PM Thompson, LE Gyllenhammer… - …, 2022 - Wiley Online Library
Objective This study tested the hypothesis, in a prospective cohort study design, that
maternal saturated free fatty acid (sFFA) concentration during pregnancy is prospectively …

[HTML][HTML] Assay optimization for the objective quantification of human multilineage colony-forming units

EN Thompson, MJ Carlino, VM Scanlon… - Experimental …, 2023 - Elsevier
Colony-forming unit (CFU) assays are a powerful tool in hematopoietic research because
they allow researchers to functionally test the lineage potential of individual stem and …