Spatial properties of tumour growth have profound implications for cancer progression,
therapeutic resistance and metastasis. Yet, how spatial position governs tumour cell division …

Recently our group and others have identified DDX41 mutations both as germ line and
acquired somatic mutations in families with multiple cases of late onset myelodysplastic …

… Lewinsohn Evolutionary and spatial dynamics underlying intra-tumor heterogeneity Maya
A. Lewinsohn A dissertation submitted in partial fulfillment of the requirements for the degree …

Most patients with epilepsy have good control of seizures using medications. However, up to
1/3 of epilepsy patients still have seizures despite trying several medications. Evidence has …

Spatial properties of tumor growth have profound implications for cancer progression,
therapeutic resistance and metastasis. Yet, how spatial position governs tumor cell division …

The sweet melon fruit is characterized by a metabolic transition during its development that
leads to extensive accumulation of the disaccharide sucrose in the mature fruit. While the …

Phylogenetics has traditionally inferred shared genetic histories of species over
macroevolutionary time. With the expansion of cancer multi-region and single-cell sequencing, …

Purpose: While the role of adaptive T cell responses in uveitis has been extensively studied,
we know little of the innate signals that precede and contribute to autoreactive T cell …

Purpose:: Mutated pyrin (encoded the MEFV gene) is the genetic cause of the inflammatory
disorder, familial Mediterranean fever (FMF). Interestingly, mutations in pyrin are prevalent in …

Plants rely on innate immunity to perceive and ward off microbes and pests, and are able to
overcome the majority of invading microorganisms. Even so, specialized pathogens …