User profiles for Maya Ghoussaini
Maya GhoussainiResearch Associate, Department of Oncology, University of Cambridge Verified email at medschl.cam.ac.uk Cited by 12812 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
INTRODUCTION The emergence of three lethal coronaviruses in <20 years and the urgency
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies, …
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies, …
Association analysis identifies 65 new breast cancer risk loci
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
…, P Hall, A Gonzalez-Neira, M Ghoussaini… - Nature …, 2013 - nature.com
Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for ∼9…
been identified as associated with susceptibility to breast cancer, and these account for ∼9…
Genome-wide association study identifies five new breast cancer susceptibility loci
…, A Renwick, M Maranian, S Seal, M Ghoussaini… - Nature …, 2010 - nature.com
Breast cancer is the most common cancer in women in developed countries. To identify
common breast cancer susceptibility alleles, we conducted a genome-wide association study in …
common breast cancer susceptibility alleles, we conducted a genome-wide association study in …
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
…, DA Leongamornlert, M Tymrakiewicz, M Ghoussaini… - Nature …, 2013 - nature.com
Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …
The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
…, S Horswell, S Young, M Ghoussaini… - Nucleic acids …, 2023 - academic.oup.com
The Open Targets Platform ( https://platform.opentargets.org/ ) is an open source resource to
systematically assist drug target identification and prioritisation using publicly available data…
systematically assist drug target identification and prioritisation using publicly available data…
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
…, SF Nielsen, MJ Maranian, M Ghoussaini… - Nature …, 2013 - nature.com
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ∼480 …
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ∼480 …
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …
Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
Open Targets Genetics ( https://genetics.opentargets.org ) is an open-access integrative
resource that aggregates human GWAS and functional genomics data including gene …
resource that aggregates human GWAS and functional genomics data including gene …
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23. 2
S Ahmed, G Thomas, M Ghoussaini, CS Healey… - Nature …, 2009 - nature.com
Genome-wide association studies (GWAS) have identified seven breast cancer susceptibility
loci, but these explain only a small fraction of the familial risk of the disease. Five of these …
loci, but these explain only a small fraction of the familial risk of the disease. Five of these …