Itch triggers scratching, a behavioural defence mechanism that aids in the removal of harmful
irritants and parasites 1 . Chemical itch is triggered by many endogenous and exogenous …

The brush of a feather and a pinprick are perceived as distinct sensations because they are
detected by discrete cutaneous sensory neurons. Inflammation or nerve injury can disrupt …

Iron overload causes progressive organ damage and is associated with arthritis, liver damage,
and heart failure. Elevated iron levels are present in 1%–5% of individuals; however, iron …

Hereditary xerocytosis is thought to be a rare genetic condition characterized by red blood
cell (RBC) dehydration with mild hemolysis. RBC dehydration is linked to reduced …

Adipose tissues communicate with the central nervous system to maintain whole-body energy
homeostasis. The mainstream view is that circulating hormones secreted by the fat convey …

Sensory neurons detect mechanical forces from both the environment and internal organs
to regulate physiology. PIEZO2 is a mechanosensory ion channel critical for touch, …

Keratinocytes, the predominant cell type of the epidermis, migrate to reinstate the epithelial
barrier during wound healing. Mechanical cues are known to regulate keratinocyte re-…

Distal arthrogryposis (DA) is a collection of rare disorders that are characterized by congenital
joint contractures. Most DA mutations are in muscle- and joint-related genes, and the …

The gastrointestinal tract is in a state of constant motion. These movements are tightly
regulated by the presence of food and help digestion by mechanically breaking down and …

The most common equine breeding practice to decrease the time to the first ovulation of the
year is to use artificial lights starting December 1 in the Northern Hemisphere. It can take 60–…