SARS-CoV-2, the cause of COVID-19, requires reliable diagnostic methods to track the
circulation of this virus. Following the development of RT-qPCR methods to meet this diagnostic …

This review summarizes our current understanding of exocrine pancreas development,
including the formation of acinar, ductal and centroacinar cells. We discuss the transcription …

Purpose To evaluate the impact of technically challenging variants on the implementation,
validation, and diagnostic yield of commonly used clinical genetic tests. Such variants include …

The COVID-19 pandemic illustrated the important role of diagnostic tests, including lateral
flow tests (LFTs), in identifying patients and their contacts to slow the spread of infections. …

PURPOSE We report the results from a Foundation for the National Institutes of Health
Biomarkers Consortium project to address the absence of well-validated quality control materials (…

Lentiviral vectors (LV) have proven to be powerful tools for stable gene delivery in both
dividing and non-dividing cells. Approval of these LVs for use in clinical applications has been …

Nucleic acid analysis is used in many areas of life sciences such as medicine, food safety,
and environmental monitoring. Accurate, reliable measurements of nucleic acids are crucial …

The intracellular protein p120 catenin aids in maintenance of cell–cell adhesion by regulating
E-cadherin stability in epithelial cells. In an effort to understand the biology of p120 catenin …

Well-characterized reference materials support harmonization and accuracy when conducting
nucleic acid-based tests (such as qPCR); digital PCR (dPCR) can measure the absolute …

Adventitious virus testing assures product safety by demonstrating the absence of viruses
that could be unintentionally introduced during the manufacturing process. The capabilities of …