Maintaining macrophage (MΦ) heterogeneity is critical to ensure intestinal tissue homeostasis
and host defense. The gut microbiota and host factors are thought to synergistically guide …

The mammalian immune system is equipped with unconventional T cells that respond to
microbial molecules such as glycolipids and small-molecule metabolites, which are invisible to …

Invariant Natural Killer T (iNKT) cells are unconventional T cells that respond to glycolipid
antigens found in microbes in a CD1d-dependent manner. iNKT cells exert innate-like …

Invariant Natural Killer T (iNKT) cells are unconventional T cells that respond to microbe-derived
glycolipid antigens. iNKT cells exert fast innate effector functions that regulate immune …

Invariant NKT (iNKT) cells are innate lipid-reactive T cells that develop and differentiate in
the thymus into iNKT1/2/17 subsets, akin to TH 1/2/17 conventional CD4 T cell subsets. The …

The microbiota is a driving force that influences host physiological functions. In this review,
we discuss some of the methods that have been used in the pursuit of relevant host–…

CD1d-restricted invariant NKT (iNKT) cells are innate-like T cells that respond to glycolipids,
a class of Ags that are invisible to conventional T cells. iNKT cells develop in the thymus …

Maintaining intestinal macrophage (MP) heterogeneity is critical to ensure tissue homeostasis
and host defense. The gut microbiota and host factors are thought to synergistically shape …

Cytotoxic cells are major effectors in adoptive cell transfer (ACT) cancer therapies. Although
autologous conventional T cells are commonly used in ACT therapies, other types of cells, …

The enormous number of commensal bacteria in the lower intestine of vertebrates share
abundant molecular patterns used for innate immune recognition of pathogenic bacteria. We …