User profiles for Mehmet Somel
Mehmet SomelMiddle East Technical University Verified email at metu.edu.tr Cited by 6551 |
Million-year-old DNA sheds light on the genomic history of mammoths
Temporal genomic data hold great potential for studying evolutionary processes such as
speciation. However, sampling across speciation events would, in many cases, require …
speciation. However, sampling across speciation events would, in many cases, require …
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA
As modern humans migrated out of Africa, they encountered many new environmental
conditions, including greater temperature extremes, different pathogens and higher altitudes. …
conditions, including greater temperature extremes, different pathogens and higher altitudes. …
[HTML][HTML] A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice
It has been proposed that two amino acid substitutions in the transcription factor FOXP2 have
been positively selected during human evolution due to effects on aspects of speech and …
been positively selected during human evolution due to effects on aspects of speech and …
[PDF][PDF] The demographic development of the first farmers in Anatolia
The archaeological documentation of the development of sedentary farming societies in
Anatolia is not yet mirrored by a genetic understanding of the human populations involved, in …
Anatolia is not yet mirrored by a genetic understanding of the human populations involved, in …
Human brain evolution: transcripts, metabolites and their regulators
M Somel, X Liu, P Khaitovich - Nature Reviews Neuroscience, 2013 - nature.com
What evolutionary events led to the emergence of human cognition? Although the genetic
differences separating modern humans from both non-human primates (for example, …
differences separating modern humans from both non-human primates (for example, …
[HTML][HTML] Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears
Polar bears are uniquely adapted to life in the High Arctic and have undergone drastic
physiological changes in response to Arctic climates and a hyperlipid diet of primarily marine …
physiological changes in response to Arctic climates and a hyperlipid diet of primarily marine …
MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain
Changes in gene expression levels determine differentiation of tissues involved in development
and are associated with functional decline in aging. Although development is tightly …
and are associated with functional decline in aging. Although development is tightly …
Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques
X Liu, M Somel, L Tang, Z Yan, X Jiang, S Guo… - Genome …, 2012 - genome.cshlp.org
Over the course of ontogenesis, the human brain and human cognitive abilities develop in
parallel, resulting in a phenotype strikingly distinct from that of other primates. Here, we used …
parallel, resulting in a phenotype strikingly distinct from that of other primates. Here, we used …
[PDF][PDF] Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes
The social organization of the first fully sedentary societies that emerged during the Neolithic
period in Southwest Asia remains enigmatic, 1 mainly because material culture studies …
period in Southwest Asia remains enigmatic, 1 mainly because material culture studies …
Transcriptional neoteny in the human brain
In development, timing is of the utmost importance, and the timing of developmental processes
often changes as organisms evolve. In human evolution, developmental retardation, or …
often changes as organisms evolve. In human evolution, developmental retardation, or …