Parkinsons Disease-redox mechanisms

J Adams Jr, ML Chang… - Current medicinal …, 2001 - ingentaconnect.com
Parkinson's disease occurs in 1percent of people over the age of 65 when about 60percent
of the dopaminergic neurons in the substantia nigra of the midbrain are lost. Dopaminergic …

Nicotinamide Offers Multiple Protective Mechanisms in Stroke as a Precursor for NAD+, as a PARP Inhibitor and by Partial Restoration of Mitochondrial Function

L Klaidman, M Morales, S Kem, J Yang, ML Chang… - Pharmacology, 2003 - karger.com
The purpose of the current study was to investigate aspects of improved bioenergetic function
using nicotinamide during stroke. Using a global ischemia-reperfusion mouse model, ATP …

Nicotinamide therapy protects against both necrosis and apoptosis in a stroke model

J Yang, LK Klaidman, ML Chang, S Kem… - Pharmacology …, 2002 - Elsevier
Background and purpose: Nicotinamide protects against brain damage in ischemia–reperfusion.
However, the dosage and time of treatment require clarification. It is also not clear if …

[HTML][HTML] Taiwanese green propolis ethanol extract delays the progression of type 2 diabetes mellitus in rats treated with streptozotocin/high-fat diet

LH Chen, YW Chien, ML Chang, CC Hou, CH Chan… - Nutrients, 2018 - mdpi.com
Taiwanese green propolis ethanol extract (TGPE) is produced only in Taiwan and has a
different composition from other types of propolis. TGPE is known for its anti-inflammation, anti-…

[HTML][HTML] Ethanolic Extract of Origanum vulgare Suppresses Propionibacterium acnes-Induced Inflammatory Responses in Human Monocyte and Mouse Ear Edema …

…, TJ Lien, WC Huang, JJ Liu, H Chang, ML Chang… - Molecules, 2018 - mdpi.com
Acne vulgaris (acne) is a common inflammatory skin disorder, and Propionibacterium acnes
plays a major role in the development and progression of acne inflammation. Herbs …

[HTML][HTML] Almonds ameliorate glycemic control in Chinese patients with better controlled type 2 diabetes: a randomized, crossover, controlled feeding trial

…, SC Li, CL Huang, AT Hsirh, SF Weng, ML Chang… - Nutrition & …, 2017 - Springer
Background Almonds can decrease glycemic index of co-consumed foods and are a rich
source for oleic acid and α-tocopherol. The aim of the randomized, crossover, controlled …

[HTML][HTML] Association between postpartum nutritional status and postpartum depression symptoms

YH Lin, CM Chen, HM Su, SC Mu, ML Chang, PY Chu… - Nutrients, 2019 - mdpi.com
Taiwanese women may practice traditional confinement after childbirth, and no study has
investigated the nutritional status and the effects of postpartum depression on such women. …

[HTML][HTML] Iron status of infants in the first year of life in northern Taiwan

…, YL Chen, LY Tsai, YT Kuo, IM Cheong, ML Chang… - Nutrients, 2020 - mdpi.com
Iron deficiency (ID) and iron deficiency anemia (IDA) typically occur in developing countries.
Notably, ID and IDA can affect an infant’s emotion, cognition, and development. Breast milk …

[HTML][HTML] Antimelanogenesis Effects of Leaf Extract and Phytochemicals from Ceylon Olive (Elaeocarpus serratus) in Zebrafish Model

…, HJ Chen, ST Chang, ML Chang, YT Ho, HT Chang - Pharmaceutics, 2021 - mdpi.com
The melanogenesis inhibition effect in zebrafish (Danio rerio) and antityrosinase activity of
the ethanolic extract and its phytochemicals from Ceylon olive (Elaeocarpus serratus Linn.) …

Nicotinamide and ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion

ML Chang, J Yang, S Kem, L Klaidman, T Sugawara… - Neuroscience …, 2002 - Elsevier
The possible ability of nicotinamide and ketamine to decrease infarction volume and DNA
fragmentation was investigated in a middle cerebral artery occlusion rat model. DNA …