KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
The Krüppel-associated box zinc finger protein (KRAB-ZFP) family diversified in mammals.
The majority of human KRAB-ZFPs bind transposable elements (TEs), however, since most …
The majority of human KRAB-ZFPs bind transposable elements (TEs), however, since most …
The arms race between KRAB–zinc finger proteins and endogenous retroelements and its impact on mammals
M Bruno, M Mahgoub… - Annual Review of …, 2019 - annualreviews.org
Nearly half of the human genome consists of endogenous retroelements (EREs) and their
genetic remnants, a small fraction of which carry the potential to propagate in the host genome…
genetic remnants, a small fraction of which carry the potential to propagate in the host genome…
[HTML][HTML] The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation
…, V Franke, LM Appel, L Walch, M Bruno… - Nature …, 2023 - nature.com
Transcription is regulated by a multitude of activators and repressors, which bind to the RNA
polymerase II (Pol II) machinery and modulate its progression. Death-inducer obliterator 3 (…
polymerase II (Pol II) machinery and modulate its progression. Death-inducer obliterator 3 (…
[HTML][HTML] PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
LM Appel, V Franke, M Bruno, I Grishkovskaya… - Nature …, 2021 - nature.com
The C-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) is a regulatory
hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 (PHF3) …
hub for transcription and RNA processing. Here, we identify PHD-finger protein 3 (PHF3) …
Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice
Meiotic crossovers result from homology-directed repair of DNA double-strand breaks (DSBs).
Unlike yeast and plants, where DSBs are generated near gene promoters, in many …
Unlike yeast and plants, where DSBs are generated near gene promoters, in many …
SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation
…, A Brachner, E Beltzung, M Bruno… - Journal of cell …, 2016 - journals.biologists.com
Sirtuin 2 (SIRT2) is an NAD-dependent deacetylase known to regulate microtubule dynamics
and cell cycle progression. SIRT2 has also been implicated in the pathology of cancer, …
and cell cycle progression. SIRT2 has also been implicated in the pathology of cancer, …
Dual histone methyl reader ZCWPW1 Facilitates repair of meiotic double strand breaks
Meiotic crossovers result from homology-directed repair of double strand breaks (DSBs).
Unlike yeast and plants, where DSBs are generated near gene promoters, in many vertebrates, …
Unlike yeast and plants, where DSBs are generated near gene promoters, in many vertebrates, …
Non-essential function of KRAB zinc finger gene clusters in retrotransposon suppression
The Krüppel-associated box zinc finger protein (KRAB-ZFP) family amplified and diversified
in mammals by segmental duplications, but the function of the majority of this gene family …
in mammals by segmental duplications, but the function of the majority of this gene family …
[CITATION][C] Author response: KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage
Author response: KRAB-zinc finger protein gene expansion in response to active
retrotransposons in the murine lineage SONAR logo Log in Sign up EN English Français Deutsch …
retrotransposons in the murine lineage SONAR logo Log in Sign up EN English Français Deutsch …
Platelets and extracellular vesicles in cancer: diagnostic and therapeutic implications
Several pieces of evidence support the role of activated platelets in the development of the
chronic inflammation-related diseases, such as atherothrombosis and cancer, mainly via the …
chronic inflammation-related diseases, such as atherothrombosis and cancer, mainly via the …