User profiles for Melanie A. Preston
 | Melanie A. PrestonPromega Corporation Verified email at promega.com Cited by 485 |
Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop
Post-transcriptional modification of the tRNA anticodon loop is critical for translation. Yeast
Trm7 is required for 2′-O-methylation of C 32 and N 34 of tRNA Phe , tRNA Trp , and tRNA …
Trm7 is required for 2′-O-methylation of C 32 and N 34 of tRNA Phe , tRNA Trp , and tRNA …
Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae
…, HH Shaheen, HY Huang, MA Preston… - Molecular biology of …, 2010 - Am Soc Cell Biol
tRNAs in yeast and vertebrate cells move bidirectionally and reversibly between the nucleus
and the cytoplasm. We investigated roles of members of the β-importin family in tRNA …
and the cytoplasm. We investigated roles of members of the β-importin family in tRNA …
[HTML][HTML] A direct capture method for purification and detection of viral nucleic acid enables epidemiological surveillance of SARS-CoV-2
Studies have demonstrated that SARS-CoV-2 RNA can be detected in the feces of infected
individuals. This finding spurred investigation into using wastewater-based epidemiology (…
individuals. This finding spurred investigation into using wastewater-based epidemiology (…
Unbiased screen of RNA tailing activities reveals a poly (UG) polymerase
Ribonucleotidyl transferases (rNTases) add untemplated ribonucleotides to diverse RNAs.
We have developed TRAID-seq, a screening strategy in Saccharomyces cerevisiae to identify …
We have developed TRAID-seq, a screening strategy in Saccharomyces cerevisiae to identify …
Architecture and dynamics of overlapped RNA regulatory networks
A single protein can bind and regulate many mRNAs. Multiple proteins with similar
specificities often bind and control overlapping sets of mRNAs. Yet little is known about the …
specificities often bind and control overlapping sets of mRNAs. Yet little is known about the …
tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae
MA Preston, S D'Silva, Y Kon, EM Phizicky - Rna, 2013 - rnajournal.cshlp.org
tRNAs are highly modified, each with a unique set of modifications. Several reports suggest
that tRNAs are hypomodified or, in some cases, hypermodified under different growth …
that tRNAs are hypomodified or, in some cases, hypermodified under different growth …
The requirement for the highly conserved G− 1 residue of Saccharomyces cerevisiae tRNAHis can be circumvented by overexpression of tRNAHis and its synthetase
MA Preston, EM Phizicky - Rna, 2010 - rnajournal.cshlp.org
Nearly all tRNA His species have an additional 5′ guanine nucleotide (G −1 ). G −1 is
encoded opposite C 73 in nearly all prokaryotes and in some archaea, and is added post-…
encoded opposite C 73 in nearly all prokaryotes and in some archaea, and is added post-…
Accurate microbiome sequencing with synthetic long read sequencing
The microbiome plays a central role in biochemical cycling and nutrient turnover of most
ecosystems. Because it can comprise myriad microbial prokaryotes, eukaryotes and viruses, …
ecosystems. Because it can comprise myriad microbial prokaryotes, eukaryotes and viruses, …
Failure to monitor ticlopidine: the case for clopidogrel
G Richardson, NP Curzen, MA Preston… - International Journal …, 2000 - Taylor & Francis
AIM: Ticlopidine remains unlicensed for use in coronary artery stenting. Haematological
monitoring at two-weekly intervals of all patients taking ticlopidine is recommended because of …
monitoring at two-weekly intervals of all patients taking ticlopidine is recommended because of …
Unbiased screen of RNA tailing enzymes at single-nucleotide resolution reveals a poly (UG) polymerase required for genome integrity and RNA silencing
Ribonucleotidyl transferases (rNTases) add non-templated ribonucleotides to diverse RNAs.
We developed a screening strategy in S. cerevisiae to identify sequences added by …
We developed a screening strategy in S. cerevisiae to identify sequences added by …