[PDF][PDF] Establishing cerebral organoids as models of human-specific brain evolution

…, MA Mostajo-Radji, E Di Lullo, B Alvarado, M Bedolli… - Cell, 2019 - cell.com
Direct comparisons of human and non-human primate brains can reveal molecular pathways
underlying remarkable specializations of the human brain. However, chimpanzee tissue is …

[PDF][PDF] Liver‐specific loss of β‐catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice

S Sekine, BYA Lan, M Bedolli, S Feng, M Hebrok - Hepatology, 2006 - Wiley Online Library
There is accumulating evidence that Wnt/β‐catenin signaling is involved in the regulation of
liver development and physiology. The presence of genetic alterations resulting in …

Embryonic expression of tenascin‐X suggests a role in limb, muscle, and heart development

GH Burch, MA Bedolli, S McDonough… - Developmental …, 1995 - Wiley Online Library
Tenascin‐X (TN‐X) is the newest member of the tenascin family of extracellular matrix proteins
and it is highly expressed in muscular tissues during development. To gain insight into …

CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients

AM Posselt, F Vincenti, M Bedolli, M Lantz… - …, 2003 - journals.lww.com
Background. The development of a noninvasive method to diagnose renal allograft rejection
could prevent the complications associated with graft biopsy and allow more accurate …

Expression of neuronal nitric oxide synthase corresponds to regions of selective vulnerability to hypoxia-ischaemia in the developing rat brain

SM Black, MA Bedolli, S Martinez, JD Bristow… - Neurobiology of …, 1995 - Elsevier
Nitric oxide (NO) has been implicated in the pathogenesis of brain injury from hypoxia-ischaemia.
In the brain, the enzyme responsible for NO synthesis is neuronal nitric oxide synthase …

Mild hypothermia reduces the inflammatory response and hepatic ischemia/reperfusion injury in rats

…, R Hirose, NJ Serkova, JL Coatney, M Bedolli… - Liver …, 2006 - Wiley Online Library
Background/Aims: Hypothermia is known to protect against ischemia/reperfusion (I/R) injury.
The mechanisms of protection are incompletely understood and a temperature threshold for …

Mild hypothermia provides significant protection against ischemia/reperfusion injury in livers of obese and lean rats

S Choi, J Noh, R Hirose, L Ferell, M Bedolli… - Annals of …, 2005 - journals.lww.com
Objective: To evaluate the effect of anesthesia induced mild systemic hypothermia on hepatic
injury in lean and obese rats during warm ischemia. Summary Background Data: Hepatic …

Targeted gene therapy with CD40Ig to induce long-term acceptance of liver allografts

GJ Chang, T Liu, S Feng, M Bedolli, RW O'rourke… - Surgery, 2002 - Elsevier
Background. The purpose of this study was to modulate the immune response of rat liver
transplant recipients by adenovirus-mediated gene transfer of CD40Ig, a secretable fusion …

Glutamine does not protect against hepatic warm ischemia/reperfusion injury in rats

J Noh, M Behrends, S Choi, MA Bedolli, J Yardi… - Journal of …, 2006 - Springer
The administration of glutamine before experimental ischemia/reperfusion (I/R) has been
shown to protect intestinal, pulmonary, and myocardial tissue by inducing heat shock proteins (…

Antitumor immunity induced by dendritic cell-based vaccination is dependent on interferon-γ and interleukin-12

JS Hiramoto, K Tsung, M Bedolli, JA Norton… - Journal of Surgical …, 2004 - Elsevier
BACKGROUND: This study was conducted to determine whether dendritic cells (DCs) pulsed
with a tumor cell lysate can effectively vaccinate against tumor cells and to establish which …