Targeting TrkB with a brain-derived neurotrophic factor mimetic promotes myelin repair in the brain

…, CMK Jun, AR Prawdiuk, M Biemond… - Journal of …, 2018 - Soc Neuroscience
Methods to promote myelin regeneration in response to central myelin loss are essential to
prevent the progression of clinical disability in demyelinating diseases. The neurotrophin …

Axonal degeneration in multiple sclerosis: defining therapeutic targets by identifying the causes of pathology

JY Lee, M Biemond, S Petratos - Neurodegenerative disease …, 2015 - Future Medicine
Current therapeutics in multiple sclerosis (MS) target the putative inflammation and immune
attack on CNS myelin. Despite their effectiveness in blunting the relapse rate in MS patients, …

Programmed death receptor 1 (PD‐1) ligand Fc fusion proteins reduce T‐cell proliferation in vitro independently of PD‐1

M Biemond, D Vremec, DHD Gray… - … and Cell Biology, 2024 - Wiley Online Library
Programmed death receptor 1 (PD‐1) is an inhibitory receptor on T cells shown to restrain T‐cell
proliferation. PD‐1 immune checkpoint blockade has emerged as a highly promising …

[PDF][PDF] Identifying the immune function of NgR in EAE and multiple sclerosis

M Bakhuraysah - 2016 - scholar.archive.org
Despite clear evidence demonstrating that the deletion of Nogo-receptor 1 (NgR1) can
protect against axonal degeneration and thus progression of experimental autoimmune …

Molecular characterization of mutant TP53 acute myeloid leukemia and high-risk myelodysplastic syndrome

…, M Rijken, PL Gradowska, BJ Biemond… - Blood, The Journal …, 2022 - ashpublications.org
Substantial heterogeneity within mutant TP53 acute myeloid leukemia (AML) and
myelodysplastic syndrome with excess of blast (MDS-EB) precludes the exact assessment of …

[HTML][HTML] Effects of oral N-acetylcysteine on oxidative stress in patients with sickle cell disease

…, CA de Borgie, J Chen, JA Lopez, BJ Biemond - Blood, 2017 - Elsevier
Oxidative stress (OS) has been demonstrated to play a central role in the pathophysiology
of sickle cell disease (SCD). The antioxidant N -acetylcysteine (NAC) is an important …

Nogo receptor-Fc delivered by haematopoietic cells enhances neurorepair in a multiple sclerosis model

S Ye, P Theotokis, JY Lee, MJ Kim, D Nheu… - Brain …, 2023 - academic.oup.com
Nogo receptor 1 is the high affinity receptor for the potent myelin-associated inhibitory factors
that make up part of the inflammatory extracellular milieu during experimental autoimmune …

[BOOK][B] Early American Silver in the Metropolitan Museum of Art

BC Wees, MH Harvey - 2013 - books.google.com
… My thanks to retired archivist Jeannie James for getting us started, and to the current archivist
James Moske and his colleagues Melissa Bowling and Barbara File for fielding seemingly …

[BOOK][B] Gender, sex, and politics: In the streets and between the sheets in the 21st century

S Tarrant - 2015 - books.google.com
… Gene Kelly Robyn Epstein Mishuana Goeman Becca Cragin Carol Conaway Tanya
Bakhru Catherine Orr Meredith Worthen Melissa Meade Lorena Russell Jill Gillespie Michelle …

Regulation of free radical outflow from an isolated muscle bed in exercising humans

DM Bailey, IS Young, J McEneny… - American Journal …, 2004 - journals.physiology.org
Incremental knee extensor (KE) exercise performed at 25, 70, and 100% of single-leg maximal
work rate (WR MAX ) was combined with ex vivo electron paramagnetic resonance (EPR) …