[HTML][HTML] Functional mechanisms underlying pleiotropic risk alleles at the 19p13. 1 breast–ovarian cancer susceptibility locus
…, Q Li, MK Delgado, JM Lee, K Aittomäki… - Nature …, 2016 - nature.com
A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here
we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 …
we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 …
PET imaging of 64Cu-DOTA-scFv-anti-PSMA lipid nanoparticles (LNPs): Enhanced tumor targeting over anti-PSMA scFv or untargeted LNPs
P Wong, L Li, J Chea, MK Delgado, D Crow… - Nuclear medicine and …, 2017 - Elsevier
Introduction Single chain (scFv) antibodies are ideal targeting ligands due to their modular
structure, high antigen specificity and affinity. These monovalent ligands display rapid tumor …
structure, high antigen specificity and affinity. These monovalent ligands display rapid tumor …
[HTML][HTML] Molecular analysis of mixed endometrioid and serous adenocarcinoma of the endometrium
…, E Pakzamir, B Liu, JM Lee, MK Delgado, K Duncan… - PLoS …, 2015 - journals.plos.org
Background The molecular biology and cellular origins of mixed type endometrial carcinomas
(MT-ECs) are poorly understood, and a Type II component of 10 percent or less may …
(MT-ECs) are poorly understood, and a Type II component of 10 percent or less may …
Mechanical regulation of cell size, fate, and behavior during asymmetric cell division
MK Delgado, C Cabernard - Current opinion in cell biology, 2020 - Elsevier
Asymmetric cell division (ACD) is an evolutionary conserved mechanism used by
prokaryotes and eukaryotes alike to generate cell diversity. ACD can be manifested in biased …
prokaryotes and eukaryotes alike to generate cell diversity. ACD can be manifested in biased …
Cell surface receptors TREM2, CD14 and integrin αMβ2 drive sinking engulfment in phosphatidylserine-mediated phagocytosis
…, AP van Loon, E Peterman, MK Delgado… - BioRxiv, 2022 - biorxiv.org
Macrophages phagocytose and thereby eliminate a wide array of extracellular threats, ranging
from antibody-coated bacteria to apoptotic cells. Precision modulation of phagocytosis …
from antibody-coated bacteria to apoptotic cells. Precision modulation of phagocytosis …
Synthesis, positron emission tomography imaging, and therapy of diabody targeted drug lipid nanoparticles in a prostate cancer murine model
P Wong, L Li, J Chea, MK Delgado, E Poku… - Cancer Biotherapy & …, 2017 - liebertpub.com
The blood clearance of chemotherapeutic drugs such as doxorubicin (Dox) can be extended
by incorporation into lipid nanoparticles (LNPs) and further improved by tumor targeting …
by incorporation into lipid nanoparticles (LNPs) and further improved by tumor targeting …
[HTML][HTML] Mass Spectrometry Defines Lysophospholipids as Ligands for Chicken MHCY Class I Molecules
…, RM Goto, S Bhattacharya, MK Delgado… - The Journal of …, 2023 - journals.aai.org
Chicken (Gallus gallus) MHCY class I molecules are highly polymorphic yet substantially
different from polymorphic MHC class I molecules that bind peptide Ags. The binding grooves …
different from polymorphic MHC class I molecules that bind peptide Ags. The binding grooves …
The impact of cancer metastases on COVID‐19 outcomes: A COVID‐19 and Cancer Consortium registry‐based retrospective cohort study
…, D Vilar‐Compte, AI Cárdenas‐Delgado… - Cancer, 2024 - Wiley Online Library
Background COVID‐19 can have a particularly detrimental effect on patients with cancer, but
no studies to date have examined if the presence, or site, of metastatic cancer is related to …
no studies to date have examined if the presence, or site, of metastatic cancer is related to …
[HTML][HTML] Impact of disaster research on the development of early career researchers: lessons learned from the wastewater monitoring pandemic response efforts
J Delgado Vela, JS McClary-Gutierrez… - … science & technology, 2022 - ACS Publications
The environmental science and engineering research community has repeatedly demonstrated
its ability to rapidly mobilize to protect human health and the environment by performing …
its ability to rapidly mobilize to protect human health and the environment by performing …
Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG+-Specific B-Cells in the Rabbit Model of …
KN Delgado, JM Montezuma-Rusca, IC Orbe… - MBio, 2022 - Am Soc Microbiol
The resurgence of syphilis in the new millennium has called attention to the importance of a
vaccine for global containment strategies. Studies with immune rabbit serum (IRS) indicate …
vaccine for global containment strategies. Studies with immune rabbit serum (IRS) indicate …