User profiles for Melissa N. Hart
 | Melissa N HartPost doctoral researcher Verified email at rvc.ac.uk Cited by 181 |
[HTML][HTML] The PfRCR complex bridges malaria parasite and erythrocyte during invasion
The symptoms of malaria occur during the blood stage of infection, when parasites invade
and replicate within human erythrocytes. The PfPCRCR complex 1 , containing PfRH5 (refs. ), …
and replicate within human erythrocytes. The PfPCRCR complex 1 , containing PfRH5 (refs. ), …
Gliding motility of Plasmodium merozoites
K Yahata, MN Hart, H Davies… - Proceedings of the …, 2021 - National Acad Sciences
Plasmodium malaria parasites are obligate intracellular protozoans that use a unique form
of locomotion, termed gliding motility, to move through host tissues and invade cells. The …
of locomotion, termed gliding motility, to move through host tissues and invade cells. The …
The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation
The efficacy of current antimalarial drugs is threatened by reduced susceptibility of Plasmodium
falciparum to artemisinin, associated with mutations in pfkelch13. Another gene with …
falciparum to artemisinin, associated with mutations in pfkelch13. Another gene with …
CRISPR-Cas9 genome editing of Plasmodium knowlesi
Plasmodium knowlesi is a zoonotic malaria parasite in Southeast Asia that can cause severe
and fatal malaria in humans. The main hosts are Macaques, but modern diagnostic tools …
and fatal malaria in humans. The main hosts are Macaques, but modern diagnostic tools …
Structure of the PfRCR complex which bridges the malaria parasite and erythrocyte during invasion
The symptoms of malaria occur during the blood stage of infection, when parasites invade
and replicate within human erythrocytes. The five-component PfPCRCR complex, containing …
and replicate within human erythrocytes. The five-component PfPCRCR complex, containing …
[HTML][HTML] Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites
MN Hart, F Mohring, SM DonVito, JA Thomas… - Nature …, 2023 - nature.com
Invasion of red blood cells (RBCs) by Plasmodium merozoites is critical to their continued
survival within the host. Two major protein families, the Duffy binding-like proteins (DBPs/EBAs…
survival within the host. Two major protein families, the Duffy binding-like proteins (DBPs/EBAs…
Modification of an atypical clathrin-independent AP-2 adaptin complex of Plasmodium falciparum reduces susceptibility to artemisinin
The efficacy of current antimalarial drugs is threatened by reduced susceptibility of Plasmodium
falciparum to artemisinin. In the Mekong region this is associated with mutations in the …
falciparum to artemisinin. In the Mekong region this is associated with mutations in the …
[PDF][PDF] Rapid and iterative genome editing in the zoonotic malaria parasite Plasmodium 2 knowlesi: New tools for P. vivax research 3
Tackling relapsing Plasmodium vivax and zoonotic Plasmodium knowlesi infections is critical
to 20 reducing malaria incidence and mortality worldwide. Understanding the biology of …
to 20 reducing malaria incidence and mortality worldwide. Understanding the biology of …
Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
10.7554/eLife.45829.001 Tackling relapsing Plasmodium vivax and zoonotic Plasmodium
knowlesi infections is critical to reducing malaria incidence and mortality worldwide. …
knowlesi infections is critical to reducing malaria incidence and mortality worldwide. …
Combining Human Epigenetics and Sleep Studies in Caenorhabditis elegans: A Cross-Species Approach for Finding Conserved Genes Regulating Sleep
Study Objectives: We aimed to test a combined approach to identify conserved genes
regulating sleep and to explore the association between DNA methylation and sleep length. …
regulating sleep and to explore the association between DNA methylation and sleep length. …